Results 71 to 80 of about 963,670 (283)
Objective To summarize the clinical phenotypes and genetic mutations of DNAJB6 related myopathies. Methods We retrospectively reviewed the clinical information, laboratory tests, muscle MRIs, electromyography results, muscle pathology examinations and ...
LI Fan +8 more
doaj
Directed evolution of enzymes at the crossroads of tradition and innovation
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
The research problem consists on the following question: how to structure an information mediation activity to work with fan and fandoms activities in school libraries?
Everton da Silva Camillo +1 more
doaj +1 more source
Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay +2 more
wiley +1 more source
Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source
Attachment to a star can manifest itself in diverse forms, from a simple trip to the cinema to private actions such as letter-writing. Gérard Philipe, widely adulated, is at the root of a wealth of correspondence.
Camille Beaujeault
doaj +1 more source
Electric fan (possibly with heating unit inside). Red louvred plastic casing with three-blade fan inside. Black flex and two pin Continental plug. Chrome integral stand. Black on/off switch at rear.. Maker: Vortice.
The Betty Smithers Design Collection at Staffordshire University +1 more
core
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley +1 more source
Pathways and pitfalls: a qualitative study of student experiences in biomedical science education
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell +8 more
wiley +1 more source
We provide a mathematical study of the modified diffusion Monte Carlo (DMC) algorithm introduced in the companion article [3]. DMC is a simulation technique that uses branching particle systems to represent expectations associated with Feynman‐Kac formulae.
Hairer, M, Weare, J
openaire +3 more sources

