Results 71 to 80 of about 2,759,336 (296)

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

Enumerating Polytropes [PDF]

open access: yes, 2016
Polytropes are both ordinary and tropical polytopes. We show that tropical types of polytropes in $\mathbb{TP}^{n-1}$ are in bijection with cones of a certain Gr\"{o}bner fan $\mathcal{GF}_n$ in $\mathbb{R}^{n^2 - n}$ restricted to a small cone called ...
Tran, Ngoc Mai
core  

The skills required for transition to university and study in biological sciences: A student perspective

open access: yesFEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

open access: yesAging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey   +12 more
wiley   +1 more source

Pratiques de fan et dynamiques culturelles

open access: yesCommunication, 2014
In order to understand how fiction can exert power over an audience, the author focuses on fans living on the island of La Réunion. Through interviews with some of the island’s youth, the author shows how fans’ practices are made all the more complex ...
Flavie Plante
doaj   +1 more source

Supersonic fan blading [PDF]

open access: yes, 1974
Radially extending rotor blades are disposed on a hub to form a supersonic propulsion fan for a turbofan engine. The peripheral spacing of the blades is such as to avoid forming a channel or passageway between adjacent blades.
Goldstein, A. W.
core   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

open access: yesAging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu   +8 more
wiley   +1 more source

Polytopal realizations of finite type $\mathbf{g}$-vector fans

open access: yes, 2018
This paper shows the polytopality of any finite type $\mathbf{g}$-vector fan, acyclic or not. In fact, for any finite Dynkin type $\Gamma$, we construct a universal associahedron $\mathsf{Asso}_{\mathrm{un}}(\Gamma)$ with the property that any $\mathbf{g}
Hohlweg, Christophe   +2 more
core  

Acoustic Measures Capture Speech Dysfunction in Spinocerebellar Ataxia

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Spinocerebellar ataxias (SCA) are hereditary cerebellar degenerative disorders with a common feature of dysarthria, involving impaired phonatory and articulatory control of speech, thereby affecting social communication. In this study, we investigated whether acoustic measures could objectively measure speech dysfunction and identify
Zena Fadel   +5 more
wiley   +1 more source

Effect of Blade Curvature on Fan Integration in Engine Cooling Module

open access: yesAcoustics, 2020
Two blade curvatures representative of those found in automotive fans are compared. Measured performances are analyzed for forward and backward curved blades, either with or without heat-exchangers placed in front of them.
Manuel Henner   +4 more
doaj   +1 more source

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