Results 101 to 110 of about 85,361 (267)

FANCD2 re-expression is associated with glioma grade and chemical inhibition of the Fanconi Anaemia pathway sensitises gliomas to chemotherapeutic agents. [PDF]

, 2014
Brain tumours kill more children and adults under 40 than any other cancer. Around half of primary brain tumours are glioblastoma multiforme (GBMs) where treatment remains a significant challenge.
Beveridge, R.D., Carroll, T.A., Collis, S.J., Cox, A., Depondt, M.L., Fernando, M., Jellinek, D., Kriplani, D.H., Myers, K.N., Patil, A.A., Roylance, A., Sayal, P.   +11 more
core   +2 more sources

Renal tubular acidosis: A ‘basic’ disorder

Equine Veterinary Education, EarlyView.
H. J. Mason, L. G. Arroyo
wiley   +1 more source

The FANCM:p.Arg658* truncating variant is associated with risk of triple-negative breast cancer. [PDF]

, 2019
Breast cancer is a common disease partially caused by genetic risk factors. Germline pathogenic variants in DNA repair genes BRCA1, BRCA2, PALB2, ATM, and CHEK2 are associated with breast cancer risk.
Aalfs, Cora M, ABCTB Investigators, Adank, Muriel A, Adlard, Julian, Agata, Simona, Agnarsson, Bjarni A, Ahearn, Thomas, Aittomäki, Kristiina, Ambrosone, Christine B, Andrews, Lesley, Anton-Culver, Hoda, Antonenkova, Natalia N, Arndt, Volker, Arnold, Norbert, Aronson, Kristan J, Arun, Banu K, Asseryanis, Ella, Auber, Bernd, Auvinen, Päivi, Azzollini, Jacopo, Balmaña, Judith, Barkardottir, Rosa B, Barnes, Daniel R, Barrowdale, Daniel, Barwell, Julian, Beane Freeman, Laura E, Beauparlant, Charles Joly, Beckmann, Matthias W, Behrens, Sabine, Benitez, Javier, Berger, Raanan, Bermisheva, Marina, Blanco, Amie M, Blomqvist, Carl, Bogdanova, Natalia V, Bogliolo, Massimo, Bojesen, Anders, Bojesen, Stig E, Bolla, Manjeet K, Bonanni, Bernardo, Borg, Ake, Brady, Angela F, Brauch, Hiltrud, Brenner, Hermann, Brüning, Thomas, Burwinkel, Barbara, Buys, Saundra S, Cadoo, Karen, Caldés, Trinidad, Caleca, Laura, Caliebe, Almuth, Caligo, Maria A, Campa, Daniele, Campbell, Ian G, Canzian, Federico, Castelao, Jose E, Catucci, Irene, Chang-Claude, Jenny, Chanock, Stephen J, Claes, Kathleen BM, Clarke, Christine L, Collavoli, Anita, Conner, Thomas A, Cox, David G, Cybulski, Cezary, Czene, Kamila, Daly, Mary B, de la Hoya, Miguel, Dennis, Joe, Devilee, Peter, Diez, Orland, Ding, Yuan Chun, Dite, Gillian S, Ditsch, Nina, Domchek, Susan M, Dorfling, Cecilia M, Dos-Santos-Silva, Isabel, Durda, Katarzyna, Dwek, Miriam, Eccles, Diana M, Ekici, Arif B, Eliassen, A Heather, Ellberg, Carolina, Eriksson, Mikael, Evans, D Gareth, Fasching, Peter A, Figlioli, Gisella, Figueroa, Jonine, Flyger, Henrik, Foulkes, William D, Friebel, Tara M, Friedman, Eitan, Gabrielson, Marike, Gaddam, Pragna, Kiiski, Johanna I, Lasheras, Sandra Viz, Leslie, Goska, Michailidou, Kyriaki, Muranen, Taru A, Pujol, Roser   +99 more
core  

Klippel–Trenaunay syndrome associated with chronic myeloid leukemia

Hematology, Transfusion and Cell Therapy, 2020
C. Coskun, T. Aksu, F. Gumruk, S. Unal
doaj   +1 more source

Recent advances in understanding hematopoiesis in Fanconi Anemia [version 1; referees: 4 approved]

F1000Research, 2018
Fanconi anemia is an inherited disease characterized by genomic instability, hypersensitivity to DNA cross-linking agents, bone marrow failure, short stature, skeletal abnormalities, and a high relative risk of myeloid leukemia and epithelial ...
Grover Bagby
doaj   +1 more source

Fanconi anemia cells with unrepaired DNA damage activate components of the checkpoint recovery process [PDF]

, 2015
International audienceBACKGROUND:The FA/BRCA pathway repairs DNA interstrand crosslinks. Mutations in this pathway cause Fanconi anemia (FA), a chromosome instability syndrome with bone marrow failure and cancer predisposition.
Azpeitia, Eugenio, Cortes, Edith, Frias, Sara, Garcia-de Teresa, Benilde, Juarez, Ulises, Mendoza, Luis, Ortiz, Rocio, Ostrosky-Wegman, Patricia, Rodriguez, Alfredo, Salazar, Ana M., Sosa, David, Torres, Leda   +11 more
core   +4 more sources

A rare variant of dyskeratosis congenita: RTEL1 defect

Hematology, Transfusion and Cell Therapy, 2020
C. Coskun, S. Unal, N. Akarsu
doaj   +1 more source

Chromosomal instability syndromes are sensitive to poly ADP-ribose polymerase inhibitors

Haematologica, 2008
Poly ADP-ribose polymerase inhibitors have been shown to target cells with homologous recombination DNA repair defects. We report that poly ADP-ribose polymerase inhibitors induces apoptosis in cells deficient in other key DNA repair components ...
Terry J. Gaymes, Sydney Shall, Farzin Farzaneh, Ghulam J. Mufti   +3 more
doaj   +1 more source

Evaluation of resveratrol and N‐acetylcysteine for cancer chemoprevention in a Fanconi anemia murine model [PDF]

, 2013
Qing‐Shuo Zhang, Laura Marquez‐Loza, Andrea M. Sheehan, Kevin Watanabe‐Smith, Laura Eaton, Eric Benedetti, Angela M. Major, Kathryn Schubert, Matthew Deater, Eric W. Joseph, Markus Grompe   +10 more
openalex   +1 more source

Cells Deficient in the Fanconi Anemia Protein FANCD2 are Hypersensitive to the Cytotoxicity and DNA Damage Induced by Coffee and Caffeic Acid [PDF]

, 2016
Epidemiological studies have found a positive association between coffee consumption and a lower risk of cardiovascular disorders, some cancers, diabetes, Parkinson and Alzheimer disease.
Burgos Morón, Estefanía, Calderón Montaño, José Manuel, Guillén Mancina, Emilio, López Lázaro, Miguel, Mateos Cordero, Santiago, Orta Vázquez, Manuel Luis   +5 more
core   +2 more sources