Results 261 to 270 of about 40,199 (345)

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open access: green, 2014
Matúš Volný
openalex   +1 more source

Prenatal Evaluation of RNU4‐2 Variants in Fetuses With Central Nervous System Anomalies

open access: yesAmerican Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Fetal central nervous system (CNS) anomalies are among the most common congenital malformations, yet the overall prenatal diagnostic yield of current genetic testing remains below 40%. Variants in RNU4‐2, a non‐coding gene encoding the U4 small nuclear RNA (snRNA), have recently been linked to a novel highly recurrent dominant ...
Yiyao Chen   +13 more
wiley   +1 more source

New approaches to treating chronic obstructive pulmonary disease with Colla corii asini

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Colla corii asini improves chronic obstructive pulmonary disease (COPD) treatment through anti‐inflammatory, antioxidant, immune‐modulatory, and lung‐nourishing effects, addressing current therapeutic challenges via multitarget mechanisms. Abstract Chronic obstructive pulmonary disease (COPD) is one of the leading causes of death and disability ...
Wenchao Zhang   +5 more
wiley   +1 more source

The hockey fans in training intervention for men with overweight or obesity: a pragmatic cluster randomised trial. [PDF]

open access: yesEClinicalMedicine
Petrella RJ   +11 more
europepmc   +1 more source

Generating golden Syrian hamsters with conditional alleles via zygote microinjection of CRISPR/Cas9

open access: yesAnimal Models and Experimental Medicine, EarlyView.
We established the first conditional knockout (cKO) model in the golden Syrian hamster by CRISPR/Cas9‐mediated genome editing. Cas9 protein, two sgRNAs, and a donor plasmid carrying loxP‐flanked exon 2 of the ApoF gene were microinjected into one‐cell embryos. The floxed allele was efficiently generated (up to 27%) and transmitted through the germline.
Wei Chen   +16 more
wiley   +1 more source

Toward Harmonizing Quantification of Dopamine Neuron Imaging Biomarkers in Parkinson's Disease: The Centamine Scale

open access: yesAnnals of Neurology, EarlyView.
Objective Dopaminergic imaging is a key biomarker for both the investigation of the biology of Parkinson's disease and related synucleinopathies and the evaluation of potential therapies in clinical trials. This work presents a harmonized approach for quantifying dopaminergic molecular imaging tracers, such as [123I]ioflupane (dopamine transporter scan
Zhen Fan   +174 more
wiley   +1 more source

Imidazolium Cation‐Stabilized Interfacial Chemistry for Durable Aqueous Cadmium‐Iodine Batteries

open access: yesAngewandte Chemie, EarlyView.
An aqueous cadmium‐iodine (Cd//I2) battery is constructed through interfacial chemistry regulation. The cadmium anode effectively suppresses parasitic hydrogen evolution and enhances anode stability, while the incorporation of BMIM+ additives anchors polyiodide species, alleviating the polyiodide shuttle effect and reinforcing interfacial robustness ...
Wenjing Li   +9 more
wiley   +2 more sources

Route of fire: Pregame rituals and emotional synchrony among Brazilian football fans. [PDF]

open access: yesProc Natl Acad Sci U S A
Xygalatas D   +3 more
europepmc   +1 more source

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