Results 31 to 40 of about 1,251,645 (259)

Nuevos medios y técnicas para la enseñanza superior: II. La enseñanza programada

open access: yesRevista Española de Pedagogía
Entre las innovaciones educativas, particular interés ha despertado la enseñanza programada, que, aunque ciertamente le queda camino por recorrer, desde su nacimiento y primer desarrollo ha constituido la esperanza de muchos de los teorizadores del ...
José Luis Fans Martín   +1 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Nuevos medios y técnicas para la enseñanza superior: l. Los medios audiovisuales

open access: yesRevista Española de Pedagogía
La mejora de los métodos de enseñanza y de aprendizaje en todos los niveles de instrucción es una necesidad que se hace cada día más urgente. También en la enseñanza universitaria se siente esta urgencia.
José Luís Fans Martín   +1 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Avulsions and the spatio-temporal evolution of debris-flow fans

open access: yes, 2018
Debris flows are water-laden masses of sediment that move rapidly through channel networks and over alluvial fans, where they can devastate people and property.
T. Haas   +6 more
semanticscholar   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Broken Windows Theory-Based Spectator Behavior Scale (BWTSBS): a validity and reliability study

open access: yesFrontiers in Psychology
PurposeThe aim of this study is to develop a scale to measure the spectator behaviors of fans and spectators. For this purpose, the research was conducted in two phases.MethodsThe sample of the study consists of 220 fans aged 18 and over who are ...
Sultan Yavuz Eroglu   +5 more
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

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