Results 71 to 80 of about 600,944 (293)

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

Integrating Smart Ceiling Fans and Communicating Thermostats to Provide Energy-Efficient Comfort [PDF]

, 2020
The project goal was to identify and test the integration of smart ceiling fans and communicating thermostats. These highly efficient ceiling fans use as much power as an LED light bulb and have onboard temperature and occupancy sensors for automatic ...
Arens, Edward, Brager, Gail, Brooks, Andy, Cohn, Sebastian, Douglas-Jaimes, David, Graham, Lindsay T, Greene, Mitch, Miller, Dana, Paliaga, Gwelen, Peffer, Therese, Present, Elaina, Raftery, Paul, Zhang, Hui   +12 more
core  

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

FAN LOYALTY IN CASES OF LOW SPORT PERFORMANCE – HOW MUCH IS TOO MUCH? [PDF]

Analele Universităţii Constantin Brâncuşi din Târgu Jiu : Seria Economie
Sport is one of the most precious elements of life. And sports competitions are part of human nature. Since ancient times, people have organized contests and eagerly awaited the outcome. Why is fan loyalty such an important factor?
POPA MARIAN GABRIEL, POPESCU MARIUS CĂTĂLIN, PĂSĂRIN LEONARDO DANIEL, DIACONESCU DRAGOȘ LAURENȚIU, SANDU VLAD ANTONIUS , COSTIN DAN EUGEN   +5 more
doaj  

Esports buffs: the perceived role of fans and fandoms in U.S. collegiate programs

Frontiers in Sports and Active Living
IntroductionCollegiate esports—organized competitive gaming—has expanded rapidly in the United States, drawing in student players, broadcasters, and support staff, as well as university employees. Universities have invested financially in esports, hoping
Amanda C. Cote, Amanda C. Cote, Md Waseq Ur Rahman, Md Waseq Ur Rahman, Maxwell Foxman, Maxwell Foxman, Andrew Wilson, Andrew Wilson, Brandon C. Harris, Brandon C. Harris, Onder Can, Onder Can, Jared C. Hansen, Jared C. Hansen   +13 more
doaj   +1 more source

Inducements of Rochester Americans Fans [PDF]

, 2017
The purpose of this research was to examine the factors that motivate minor league sports fans. Specifically, this research was designed to analyze the factors that influence a fan’s motivation to attend Rochester Americans games.
D\u27Agostino, Alex
core   +1 more source

The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential

Aging and Cancer, EarlyView.
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley   +1 more source

A INDÚSTRIA 4.0 E AS INOVAÇÕES EM SUPRIMENTOS

Faces: Revista de Administração
O departamento de suprimentos de uma empresa é o responsável por atender as necessidades organizacionais com o intuito de gerar a integração e o desenvolvimento da organização.
Frederico Cesar Mafra Pereira, Marcelo Agenor Espíndola, Bráulio Alaor da Silva Queiroz   +2 more
doaj  

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source