Results 61 to 70 of about 116,168 (286)

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

open access: yesFEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay   +2 more
wiley   +1 more source

FUTBOL TARAFTARLARININ MARKA DEĞERİ YARATMALARI ÜZERİNE BİR ARAŞTIRMA

open access: yesSelçuk Üniversitesi Sosyal Bilimler Enstitüsü Dergisi, 2007
Bu araştırmanın amacı; profesyonel spor kulüplerinin marka değerine tüketicilerin verdikleri katkıdüzeylerini belirlemektir. Bu amaçla profesyonel spor kulüplerinin tüketicisi konumunda olan taraftarlar, farklıkriterlere göre analiz edilmiştir ...
Özden Taşğın, Murat Tekin
doaj  

The Brownian Fan

open access: yesCommunications on Pure and Applied Mathematics, 2014
We provide a mathematical study of the modified diffusion Monte Carlo (DMC) algorithm introduced in the companion article [3]. DMC is a simulation technique that uses branching particle systems to represent expectations associated with Feynman‐Kac formulae.
Hairer, M, Weare, J
openaire   +3 more sources

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

Influence of design parameters on the global performances of low-speed counter-rotating axial-flow fans [PDF]

open access: yes, 2014
The present work aims at experimentally investigating the effects of some parameters on the performances of a counter-rotating stage, and on the instationary flow between the rotors.
BAKIR, Farid   +5 more
core   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Interactivité, resémantisation, et plaisirs de la primauté ontologique : les œuvres de fans comme centre du récit

open access: yesRevue Française des Sciences de l’Information et de la Communication, 2017
Under many circumstances, fan works do not merely add to a central commercial narrative, but instead become the definitive version of « what really happened » for some members of the audience.
Anne Kustritz
doaj   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

open access: yesFEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell   +8 more
wiley   +1 more source

Esports buffs: the perceived role of fans and fandoms in U.S. collegiate programs

open access: yesFrontiers in Sports and Active Living
IntroductionCollegiate esports—organized competitive gaming—has expanded rapidly in the United States, drawing in student players, broadcasters, and support staff, as well as university employees. Universities have invested financially in esports, hoping
Amanda C. Cote   +13 more
doaj   +1 more source

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