Results 131 to 140 of about 64,984 (332)

Plasma Proteome Reflects Tissue Damage and Clinical Manifestations in Patients With Inflammatory Myopathies

Arthritis &Rheumatology, EarlyView.
Objective Tissue‐specific biomarkers that are reliable and associated with clinical manifestations of idiopathic inflammatory myopathy (IIM) are lacking. The blood circulation in individuals serves as a central conduit, allowing communication between tissues and facilitating clearance and recycling of tissue‐derived proteins.
Yue‐Bei Luo, Josefin Kenrick, Angeles S. Galindo‐Feria, Antonella Notarnicola, Ana Daniela Ulloa Navas, Irene Peralta‐Garcia, Orane Demuynck, Andrea Kemp, Valérie Leclair, Karin Lodin, Eveline Van Gompel, Lara Dani, Fabricio Espinosa‐Ortega, Maryam Dastmalchi, Leonid Padyukov, Charlotta Preger, María Bueno Álvez, Mathias Uhlén, Peter Nilsson, Fredrik Edfors, Lina‐Marcela Diaz‐Gallo, Elisa Pin, Ingrid E. Lundberg, Begum Horuluoglu   +23 more
wiley   +1 more source

Paediatric development of radiopharmaceutical imaging agents and radioligand therapeutics

British Journal of Clinical Pharmacology, EarlyView.
Abstract This review focuses on the development of radiopharmaceutical imaging agents and radioligand therapeutics for paediatric use. Nuclear medicine plays an important role in the diagnosis and treatment of various childhood conditions, including cancers, infections and brain disorders.
Justin L. Hay, Amandine Manon, Hunter Stephens, S. Y. Amy Cheung, Bart de Keizer, Erik T. te Beek   +5 more
wiley   +1 more source

Understanding the Cancer-Associated Fibroblast (CAF) and Its Biomarker Fibroblast Activation Protein (FAP), and Aspects in Human Liver Cancer

Frontiers in Bioscience-Landmark
Tumours contain many fibroblasts, endothelial cells, and leukocytes that are emerging as therapeutic targets complementary to targeting genetically unstable cancer cells.
Yiqun Amy Qu, JiaLi C. Huang, Ziqi V. Wang, Angela L. Ferguson, Jasmine Minh Hang Nguyen, MingChang Zhang, Katharine A. Osborne, Badwi B. Boumelhem, Geoffrey W. McCaughan, Ken Liu, Mark D. Gorrell   +10 more
doaj   +1 more source

Primeira lei tonal: função harmônica nas óticas funcional e tradicional - um breve estudo comparativo

InCantare, 2015
A harmonia funcional, vertente da teoria harmônica divulgada no Brasil pelo compositor e professor Hans Joachim Koellreuter, obteve ampla difusão no meio acadêmico deste paí­s e exerceu influência entre professores e estudantes de música. Atualmente, ao
Francisco Koetz Wildt
doaj   +1 more source

FAP related periampullary adenocarcinoma

International Journal of Surgery Case Reports, 2013
The risk of periampullary neoplasia in patients with familial adenomatous polyposis (FAP) is significantly increased compared to the general population.We herein report the case of a 47-year-old woman with classic familial adenomatous polyposis with a history of total proctocolectomy for FAP who presented with an ulcerous ampullary lesion 8 years after
Mantas, D., Charalampoudis, P., Nikiteas, N.   +2 more
openaire   +3 more sources

Combinatorial Metabolic Engineering of Alkane Biosynthesis in the Osmotolerant Yeast Debaryomyces hansenii CBS 767

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Debaryomyces hansenii is a yeast with diverse potential applications like producing oleochemicals from biomass. Yet, combinatorial metabolic engineering in D. hansenii is limited because, like many nonconventional organisms, key genomic data and genetic elements are missing. Here, we report phenotypic characterization, genomic integration loci,
Zekun Li, Nilesh Kumar Sharma, Sarah Weintraub, Eric Young   +3 more
wiley   +1 more source

IJCM_400A: Perception towards family adoption programme among MBBS students of a medical college - A cross sectional study

Indian Journal of Community Medicine
Background: National Medical Commission (NMC) in their recent notification included the Family Adoption Program (FAP) in the undergraduate medical curriculum to provide a learning opportunity towards community- based health care to Indian Medical ...
Pramod, Shashidhar S. Basagoudar, Rahul C. Kirte   +2 more
doaj   +1 more source

From pathogen to “living drug factory” innovative strategies and clinical translation of bacteria as programmable intelligent vectors for cancer therapy

BMEMat, EarlyView.
Engineered bacteria serve as smart, living therapeutics that target tumors, deliver drugs, and remodel immunosuppressive microenvironments. This review highlights their potential to potentiate immunotherapy, radiotherapy, and chemotherapy, offering a promising paradigm for precise and synergistic cancer treatment. Abstract The dynamic interplay between
Haonan Shen, Weichen Zhang, Gaoli Niu, Li Wang, Ruiyan Li, Yueyue Fan, Feixue Lu, Lingling Xu, Xiaoyuan Ji, Yong Kang   +9 more
wiley   +1 more source

Syntheses, Structural Determination, and Electrochemistry of Ru₂(Fap)₄Cl and Ru₂(Fap)₄(NO)Cl

, 2016
Ru2(Fap)4Cl and Ru2(Fap)4(NO)Cl, where Fap is the 2-(2-fluoroanilino)pyridinate anion, were synthesized, and their structural, electrochemical, and spectroscopic properties were characterized.
Julien Wellhoff (2406253), John L. Bear (1776229), Guy Royal (1966873), Eric Van Caemelbecke (1776232), Karl M. Kadish (1431214), Sonia Eapen (2963391)   +5 more
core   +2 more sources

FAP Promotes Immunosuppression by Cancer-Associated Fibroblasts in the Tumor Microenvironment via STAT3-CCL2 Signaling.

Cancer Research, 2016
Cancer-associated fibroblasts (CAF) are components of the tumor microenvironment whose contributions to malignant progression are not fully understood. Here, we show that the fibroblast activation protein (FAP) triggers induction of a CAF subset with an ...
Xu-Guang Yang, Yuli Lin, Ying-Hong Shi, Bingji Li, Wei-Ren Liu, W. Yin, Yong-Jun Dang, Y. Chu, Jia Fan, R. He   +9 more
semanticscholar   +1 more source