Results 221 to 230 of about 64,984 (332)

Evaluating [¹⁸F]-AlF-FAPI-74 PET/CT for diagnosis of the unfavourable CMS4 colorectal cancer subtype (FoCus study): protocol for a prospective, observational, proof-of-concept clinical study. [PDF]

BMJ Open
van Duijvenvoorde M, Kranenburg O, van den Bos M, Hagendoorn J, Roodhart JML, Milne AN, Te Riele WW, Lange MM, Swijnenburg RJ, Arensman R, Verheijen PM, Schiphorst AHW, Kool W, Ververs T, De Keizer B, Lacle MM, Lam MGEH, Elias SG.   +17 more
europepmc   +1 more source

Scaling temporal resolution from mice to humans: Challenges and innovations in preclinical imaging of translational models

The Journal of Physiology, EarlyView.
Abstract figure legend Temporal scaling physiology differs significantly between mice and humans. Mice have higher metabolism, heart and respiratory rate, as well as faster blood flow rates, brain activity and physiological dynamics over time. These differences influence the temporal resolution needed in preclinical imaging of mouse models to ...
Sara Gargiulo, Matteo Gramanzini
wiley   +1 more source

Cancer‐associated fibroblast heterogeneity across solid and haematological malignancies: Lessons from colorectal cancer and multiple myeloma

The Journal of Physiology, EarlyView.
Abstract figure legend CAF origins and plasticity give rise to distinct phenotypes with immunosuppressive functions in colorectal cancer and multiple myeloma. These distinct CAF phenotypes contribute to immunosuppressive tumour microenvironments through ECM remodelling, cytokine signalling and immune regulation.
Hui Mo, Haoyan Han, Michael O'Dwyer, Eileen Reidy, Aideen E. Ryan   +4 more
wiley   +1 more source

Cancer-associated fibroblasts and immune evasion in endometrial cancer: current evidence and therapeutic perspectives. [PDF]

Med Oncol
Zhan J, Yan Z, Cao Z, Wu F, Wang Y, Zhan Y.   +5 more
europepmc   +1 more source

Desmoid Fibromatosis of the Gastric Wall Mimicking Needle Tract Seeding after Endoscopic Ultrasound‐Guided Fine‐Needle Biopsy for Pancreatic Cancer: A Case Report

DEN Open, Volume 7, Issue 1, April 2027.
ABSTRACT Endoscopic ultrasound‐guided fine‐needle biopsy (EUS‐FNB) is widely used for the pathological diagnosis of pancreatic diseases. However, needle tract seeding (NTS) remains a clinical concern, particularly when the puncture route is not included in the surgical resection field. We report a case in which distinguishing NTS from other pathologies
Kazuya Koyama, Kenji Takahashi, Hidemasa Kawabata, Yusuke Ono, Nobue Tamamura, Tetsuhiro Okada, Hidetaka Iwamoto, Mishie Tanino, Mikihiro Fujiya, Yusuke Mizukami   +9 more
wiley   +1 more source

The FAP × CD3 bispecific antibody OMTX305 induces T cell-mediated antitumor effects in patient-derived ex vivo models of solid tumors. [PDF]

Sci Adv
Thiel J, Schlegel JA, Liang C, Mürdter TE, Kneer A, Dreher S, Schäfer A, Seifert O, Kühl L, Preissler G, Simon L, Fabre M, Egaña I, Kurz KS, Ott G, Kontermann RE, Aulitzky WE, Schwab M, Olayioye MA, Dong M.   +19 more
europepmc   +1 more source

Worst Histology‐Based Risk Stratification for Lymph Node Metastasis in Patients With T1b Colorectal Cancer: A Retrospective Pathology‐based Study

DEN Open, Volume 7, Issue 1, April 2027.
This study evaluates a pathology‐based refinement of lymph node metastasis risk stratification in pT1b colorectal cancer. Compared with the conventional dominant histologybased assessment, a worst histologybased approach focused on poorly differentiated adenocarcinoma, combined with submucosal invasion depth and lymphatic invasion, more effectively ...
Satomi Shibata, Shin‐ichiro Horiguchi, Koichi Koizumi, Daichi Sadato, Ryoko Shimizuguchi, Akinari Takao, Jun Nakahodo, Yawara Kubota, Itaru Kubota, Hiroki Kato, Misato Takao, Daisuke Nakano, Kazushige Kawai, Tatsuro Yamaguchi, Tsunekazu Hishima, Toshiro Iizuka   +15 more
wiley   +1 more source

Correlation of apparent diffusion coefficient, FAP expression in IHC and [⁶⁸Ga]Ga‑FAPI‑46 uptake using integrated PET/MRI in high-grade soft tissue sarcoma: initial exploratory results. [PDF]

EJNMMI Res
Hettler M, Menge F, Ludwig J, Nörenberg D, Schönberg SO, Hinterberger A, Wängler B, Wängler C, Rudolf H, Davarci G, Cieslik P, Cotarelo CL, Harbrücker M, Reißfelder C, Jakob J, Kunz WG, Grawe F.   +16 more
europepmc   +1 more source

Somatic Mosaic AXIN2‐associated Colonic Polyposis Predominantly Involving the Proximal Colon: A Case Report

DEN Open, Volume 7, Issue 1, April 2027.
ABSTRACT Colonic adenomatous polyposis is most commonly caused by germline pathogenic variants in the APC gene; however, recent genetic studies have identified patients without APC mutations. AXIN2‐associated colonic polyposis is a rare condition related to dysregulation of the Wnt/β‐catenin signaling pathway. Most reported cases have involved germline
Takashi Murakami, Masami Arai, Hidetaka Eguchi, Yuka Hirasawa, Wataru Hata, Yudai Otsuki, Tomonori Yamauchi, Eiji Kamba, Takashi Yao, Akihito Nagahara   +9 more
wiley   +1 more source

FAP-Associated Cribriform Morular Thyroid Carcinoma: A Warning Sign for Sigmoid Colon Cancer. [PDF]

United European Gastroenterol J
Liu X, Lin X, Ju M, Liu Q.
europepmc   +1 more source