Results 81 to 90 of about 64,984 (332)

CEFALEIA PROLONGADA E DERRAME CEREBELAR COMO APRESENTAÇÃO INICIAL DE MIELOMA MÚLTIPLO DE TIPO IGA

Hematology, Transfusion and Cell Therapy, 2021
Descrita como possibilidade de sintoma de Mieloma Múltiplo (MM), a cefaleia, quando presente, costuma estar associada a sintomas neurológicos mais exuberantes – como neuropatias cranianas ou espinhais.
LGO Correia, FAP Ramos
doaj   +1 more source

Immunohistochemical FAP Expression Reflects 68Ga-FAPI PET Imaging Properties of Low- and High-Grade Intraductal Papillary Mucinous Neoplasms and Pancreatic Ductal Adenocarcinoma

Journal of Nuclear Medicine
Visual Abstract Pancreatic intraductal papillary mucinous neoplasms (IPMNs) are grossly visible (typically > 5 mm) intraductal epithelial neoplasms of mucin-producing cells, arising in the main pancreatic duct or its branches.
A. Spektor, E. Gutjahr, Matthias Lang, F. Glatting, T. Hackert, T. Pausch, C. Tjaden, M. Schreckenberger, U. Haberkorn, M. Röhrich   +9 more
semanticscholar   +1 more source

68Ga-FAPI PET/CT: Biodistribution and Preliminary Dosimetry Estimate of 2 DOTA-Containing FAP-Targeting Agents in Patients with Various Cancers

Journal of Nuclear Medicine, 2018
Fibroblast activation protein (FAP) is overexpressed in cancer-associated fibroblasts of several tumor entities. The recent development of quinoline-based PET tracers that act as FAP inhibitors (FAPIs) demonstrated promising results preclinically and ...
F. Giesel, C. Kratochwil, T. Lindner, Manfred M. Marschalek, A. Loktev, W. Lehnert, J. Debus, D. Jäger, P. Flechsig, A. Altmann, W. Mier, U. Haberkorn   +11 more
semanticscholar   +1 more source

The fluorogen-activating protein (FAP) biosensor system.

, 2017
CXCR4 is expressed as a fusion protein with α-FAP and US27 is expressed as a fusion protein with β-FAP, which each bind with high affinity to distinct membrane impermeable fluorogen dyes.
Juliet V. Spencer (521467), Jordan M. Boeck (3753700)   +1 more
core   +1 more source

FAP system.

, 2022
Settings of the FAP system, pen design and force data obtained in one trial from the control group.
Cheng-Feng Lin (9549770), Jin-Wei Liu (5871209), Chieh-Hsiang Hsu (12936969), Yu-Chen Lin (797541), Hsiu-Yun Hsu (448375), Chien-Hsien Yeh (12936972), Li-Chieh Kuo (394990)   +6 more
core   +1 more source

Radiosynthesis and Preclinical Evaluation of Bispecific PSMA/FAP Heterodimers for Tumor Imaging

Pharmaceuticals, 2022
Due to tumor heterogeneity and complex tumor–stromal interactions in multicellular systems, the efficiency of monospecific tracers for tumor diagnosis and therapy is currently limited. In light of the evidence of prostate-specific membrane antigen (PSMA)
Kong-Zhen Hu, Li Li, Yong Huang, Shimin Ye, Jiawei Zhong, Qingsong Yan, Yu-Hua Zhong, Lilan Fu, Pengju Feng, Ho Cheung William Li   +9 more
semanticscholar   +1 more source

Single‐Nucleus Atlas of Spinal Sarcopenia Patients Reveals Disruption of Quiescent and Regenerative Satellite Cell Niches in Fatty‐Infiltrated Muscle

Advanced Science, EarlyView.
Mechanisms of Fatty Infiltration and Muscle Degeneration. Clinical metadata identified intramuscular fat accumulation as an independent driver of muscle mass decline. Single‐nucleus RNA sequencing of spinal sarcopenia muscle revealed adipogenic reprogramming of fibro‐adipogenic progenitors, satellite‐cell niche disruption, and elevated levels of the ...
Wenkai Wu, Renxian Wang, Dingding Wang, Quanzhong Ren, Ling Wang, Fangfang Duan, Guihe Yang, Ruixuan Yu, Yi Wang, Yingyu Zhang, Zetong Zang, Chuqi Li, Weijia Liu, Wenshuang Zhang, Yi Yuan, Zitong Cheng, Xiaoguang Cheng, Junbo Liang, Yajun Liu   +18 more
wiley   +1 more source

Neonatal Gardner Fibroma Leads to Detection of Familial Adenomatous Polyposis: Two Case Reports

European Journal of Pediatric Surgery Reports, 2016
Gardner fibromas (GFs) have only recently been described as poorly circumscribed tumor-like lesions, which are exceedingly rare in children. GFs are associated with APC gene mutations and therefore with familial adenomatous polyposis (FAP).
Mattias Schäfer, Martina Kadmon, Wolfgang Schmidt, Irmgard Treiber, Ute Moog, Christian Sutter, Maximilian Stehr   +6 more
doaj   +1 more source

Senescent Fibroblasts Drive FAP/OLN Imbalance Through mTOR Signaling to Exacerbate Inflammation and Bone Resorption in Periodontitis

Advancement of science
Fibroblast activation protein (FAP), predominantly expressed in activated fibroblasts, plays a key role in inflammatory bone diseases, but its role in periodontitis remains unclear.
Chenghu Yin, Liang-Liang Fu, Shuling Guo, You-De Liang, Taizhi Shu, Wen-Jun Shao, H. Xia, Ting Xia, Min Wang   +8 more
semanticscholar   +1 more source

Glucocorticoid Receptor Signaling in Myeloid Cells Orchestrates Inflammation Resolution and Muscle Repair

Advanced Science, EarlyView.
Glucocorticoids (GC) are widely used to reduce inflammation. We show that the glucocorticoid receptor in myeloid cells regulates macrophage cell cycle and genome integrity during muscle regeneration. We demonstrate that dexamethasone administration during the early inflammatory phase delays muscle repair by increasing macrophage proliferation ...
Sirine Souali‐Crespo, Joe G. Rizk, Emilia Calvano, Rajesh Sahu, Emina Colovic, Imane Chabba, Valentine Gilbart, Erwan Grandgirard, Bastien Morlet, Qingshuang Cai, Daniel Metzger, Delphine Duteil   +11 more
wiley   +1 more source