Results 31 to 40 of about 1,542 (252)
Inelastic displacement ratio for rocking buildings subjected to far-field and near-field pulse-like ground motions [PDF]
Journal of Structural and Construction Engineering, 2019 Self centering rocking buildings are capable of reducing permanent damage and concentrating damage to replaceable energy dissipation devices. This paper aims to calculate inelastic displacement ratio for self centering rocking buildings under far field ...
Navid Rahgozar +1 more
doaj +1 more source
Shock and Vibration, 2021 Seismic analysis of tunnels close to or crossing seismogenic faults is a complex problem, which is often neglected at the design stage for the lack of specific codes or guidelines and also because underground structures are considered less vulnerable ...
Xiancheng Mei, Qian Sheng, Zhen Cui
doaj +1 more source
Walailak Journal of Science and Technology, 2020 The near-fault earthquakes ground motion usually observed a few kilometers away from the active faults generally contains high energetic velocity pulses as a consequence of directivity effects.
Yan Naung KO, Teraphan ORNTHAMMARATH
doaj +3 more sources
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Discerning protein pools by selective staining with self‐labeling tags
FEBS Letters, EarlyView.Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Bulletin of Earthquake Engineering, 2015 This study investigates the effects of near and far fault ground motion on the seismic behavior of historical arch bridges through a combined numerical and experi- mental evaluation. The approach undertaken begins with finite element modeling of the arch bridge and identification of the most significant vibration modes of the bridge through ambient ...
Sevim, Baris +3 more
openaire +3 more sources
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Civil Engineering Journal, 2018 In this study, the dynamic response of bridges to earthquakes near and far from the fault has been investigated. With respect to available data and showing the effects of key factors and variables, we have examined the bridge's performance. Modeling a two-span concrete bridge in CSI Bridge software and ability of this bridge under strong ground motion ...
Mohammad Hajali +2 more
openaire +2 more sources
Heterotropic regulation and negative homotropic cooperativity
FEBS Open Bio, EarlyView.We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea +5 more
wiley +1 more source