Results 121 to 130 of about 2,487,421 (286)

Light-regulated plant growth and development. [PDF]

, 2010
Plants are sessile and photo-autotrophic; their entire life cycle is thus strongly influenced by the ever-changing light environment. In order to sense and respond to those fluctuating conditions higher plants possess several families of photoreceptors ...
Fankhauser, C., Hornitschek, P., Kami, C., Lorrain, S.   +3 more
core   +1 more source

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky, Cara Joyce, H. Jeremy Bockholt, Paul A. Rudnick, William H. Adams, Fiona McAllister, Justin W. Smock, Michael A. Newton, Jane S. Paulsen   +8 more
wiley   +1 more source

Comparative functional analysis of full-length and N-terminal fragments of phytochrome C, D and E in red light-induced signaling. [PDF]

, 2013
Phytochromes (phy) C, D and E are involved in the regulation of red/far-red light-induced photomorphogenesis of Arabidopsis thaliana, but only limited data are available on the mode of action and biological function of these lesser studied phytochrome ...
Kircher, Stefan, Liu, Peng, Mérai, Zsuzsanna, Nagy, Ferenc István, Viczián, András, Ádám, Éva   +5 more
core   +1 more source

Real‐World Performance of CSF Kappa Free Light Chains in the 2024 McDonald Criteria

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Kappa free light chains (KFLCs) in the cerebrospinal fluid (CSF) have a similar performance to CSF‐restricted oligoclonal bands (OCB) for multiple sclerosis (MS) diagnosis. To help with implementation, we set out to resolve several remaining uncertainties: (1) performance in a real‐world cohort and the 2024 McDonald criteria; (2 ...
Maya M. Leibowitz, Ryan Cooper, Stefania Kaninia, Kathryn I. Challis, Will Greenway, Maria Bonello, Mahmoud Elbahnasawi, Deborah T. Shode, Dominika Gajdasik, Victor Iliev, Alison M. E. Whitelegg, Ian Galea   +11 more
wiley   +1 more source

Monomerization of Far-Red Fluorescent Proteins [PDF]

, 2018
Anthozoa-class red fluorescent proteins (RFPs) are frequently used as biological markers, with far-red (λ_(em) ∼ 600–700 nm) emitting variants sought for whole-animal imaging because biological tissues are more permeable to light in this range. A barrier
Brown, Kevin S., Campbell, Robert E., Gillespie, Sarah K., Hutchins, Nicholas, Mayo, Stephen L., McIsaac, R. Scott, Shen, Yi, Wannier, Timothy M., Wu, Sheng-Yi   +8 more
core   +1 more source

Complementation of the embryo-lethal T-DNA insertion mutant of AUXIN-BINDING-PROTEIN 1 (ABP1) with abp1 point mutated versions reveals crosstalk of ABP1 and phytochromes [PDF]

, 2014
The function of the extracytoplasmic AUXIN-BINDING-PROTEIN1 (ABP1) is largely enigmatic. We complemented a homozygous T-DNA insertion null mutant of ABP1 in Arabidopsis thaliana Wassilewskia with three mutated and one wild-type (wt) ABP1 cDNA, all tagged
Effendi, Yunus, Ferro, Noel, Geisler, Markus, Labusch, Corinna, Scherer, Günther F. E.   +4 more
core   +2 more sources

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende, Emilien Petit, Young Woo Park, Sophie Tezenas du Montcel, James M. Joers, Jonathan M. DuBois, H. Moore Arnold, Michal Povazan, Ipek Özdemir, Guita Banan, Romain Valabregue, Philipp Ehses, Jennifer Faber, Chiadi U. Onyike, Peter B. Barker, Jeremy D. Schmahmann, Eva‐Maria Ratai, Sub H. Subramony, Thomas H. Mareci, Khalaf O. Bushara, Henry Paulson, Thomas Klockgether, Alexandra Durr, Tetsuo Ashizawa, Christophe Lenglet, Gülin Öz, READISCA Investigators   +26 more
wiley   +1 more source

The Photoconductivity of Chloroplasts and the Far Red Light Effect

Biophysical Journal, 1960
The photoconductivity of chloroplast films in the dry and the wet state has been investigated. These films were found to behave like typical semiconductors, in agreement with the results of Arnold and co-workers, who have used only dry films. It was found that a steady photocurrent produced in a chloroplast film by blue or red light, can be either ...
openaire   +2 more sources

Structure–Function Decoupling of the Sensorimotor and Default Mode Networks in Black Americans With MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Multiple sclerosis (MS) exhibits racially disparate rates of disease progression. Black people with MS (B‐PwMS) experience a more severe disease course than non‐Hispanic White people with MS (NHW‐PwMS). Here we investigated structural and functional connectivity as well as structure–function decoupling in the ...
Emilio Cipriano, Giacomo Boffa, Maria Petracca, Marta Ponzano, Nicole Graziano, Claire Wigley, Claire Riley, Jonathan Howard, Pietro Bontempi, Sylvia Klineova, Fred Lublin, Matilde Inglese   +11 more
wiley   +1 more source

Na-O Anticorrelation and HB. IV. Detection of He-rich and He-poor stellar populations in the globular cluster NGC 6218

, 2007
We used the multifiber spectrograph FLAMES on the ESO Very Large Telescope UT2 to derive atmospheric parameters, metallicities and abundances of O and Na for 79 red giant stars in the Galactic globular cluster NGC 6218 (M 12).
A. Bragaglia, Alonso, Alonso, Asplund, Bragaglia, Brodie, Buonanno, Buonanno, Buonanno, Cardelli, Carretta, Carretta, Carretta, Carretta, Cayrel, Charbonnel, Cohen, De Angeli, De Marchi, Dinescu, E. Carretta, E. Sabbi, F. D'Antona, F. Leone, G. Catanzaro, G. James, G. Piotto, Gratton, Gratton, Gratton, Gratton, Gratton, Gratton, Hargis, Harris, Jasniewicz, Johnson, Klochkova, Kraft, Magain, Momany, P. François, Paltrinieri, Pasquini, Pilachowski, Pritzl, R. Claudi, R. G. Gratton, Ramirez, Robin, Rosenberg, Rutledge, S. Cassisi, Salaris, Salaris, Skrutskie, Smith, Sneden, Ventura, Zinn   +59 more
core   +2 more sources