Results 81 to 90 of about 2,487,421 (286)
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Time-of-flight resolved light field fluctuations reveal deep human tissue physiology. [PDF]
, 2020 Red blood cells (RBCs) transport oxygen to tissues and remove carbon dioxide. Diffuse optical flowmetry (DOF) assesses deep tissue RBC dynamics by measuring coherent fluctuations of multiply scattered near-infrared light intensity.
Du Le, VN +4 more
core
An Arabidopsis Mutant Hypersensitive to Red and Far-Red Light Signals [PDF]
The Plant Cell, 1998 A new mutant called psi2 (for phytochrome signaling) was isolated by screening for elevated activity of a chlorophyll a/b binding protein-luciferase (CAB2-LUC) transgene in Arabidopsis. This mutant exhibited hypersensitive induction of CAB1, CAB2, and the small subunit of ribulose-1,5-bisphosphate carboxylase (RBCS) promoters in the very low fluence ...
T, Genoud +6 more
openaire +2 more sources
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Quantification of non-Q B -reducing centers in leaves using a far-red pre-illumination [PDF]
, 2018 An alternative approach to quantification of the contribution of non-QB-reducing centers to Chl a fluorescence induction curve is proposed. The experimental protocol consists of a far-red pre-illumination followed by a strong red pulse to determine the ...
Schansker, Gert, Strasser, Reto
core
Radial Velocity Curves of Ellipsoidal Red Giant Binaries in the Large Magellanic Cloud [PDF]
, 2015 Ellipsoidal red giant binaries are close binary systems where an unseen, relatively close companion distorts the red giant, leading to light variations as the red giant moves around its orbit.
Nie, J. D., Wood, P. R.
core +2 more sources
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Creation of a Bose-condensed gas of rubidium 87 by laser cooling
, 2017 We demonstrate direct laser cooling of a gas of rubidium 87 atoms to quantum degeneracy. The method does not involve evaporative cooling, is fast, and induces little atom loss.
Chen, Wenlan +5 more
core +1 more source
Three-Color Protein Photolithography with Green, Red, and Far-Red Light. [PDF]
SmallAbstractProtein photolithography is an invaluable tool for generating protein microchips and regulating interactions between cells and materials. However, the absence of light‐responsive molecules that allow for the copatterning of multiple functional proteins with biocompatible visible light poses a significant challenge.
Zheng Y +4 more
europepmc +3 more sources