Results 91 to 100 of about 5,465,744 (330)
Molecular Oncology, EarlyView.This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad +17 more
wiley +1 more source
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
SocietiesThis article identifies the structural factors underlying the rise of the Populist Radical Right (PRR) in Europe and evaluates its implications for liberal democracies. Our research finds that the emergence of the PRR is driven by the decay of democratic
Alfonso A. López-Rodríguez +1 more
doaj +1 more source
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Regulating hate speech online [PDF]
, 2010 The exponential growth in the Internet as a means of communication has been emulated by an increase in far-right and extremist web sites and hate based activity in cyberspace.
Banks, James
core +1 more source
Molecular Oncology, EarlyView.The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués +3 more
wiley +1 more source
The Far Right Honeytrap: Georgian Media and the Mediagenic Far Right
, 2020 The recent wave of far-right mobilization across the globe, including Georgia, naturally attracts wide media attention. Although the interrelation of the media and the far right, especially in the Georgian context, remains under-researched, evidence from other countries shows the potential impact of media coverage on both public opinion, i.e.
openaire +2 more sources
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Far‐Right Illiberalism in the European Parliament
Politics and GovernanceThe rise of illiberalism has become a global concern, especially since the establishment of far‐right illiberal regimes in countries such as Hungary, India, Poland, and Turkey.
Larissa Böckmann +3 more
doaj +1 more source
Book review: angry white people: coming face-to-face with the British far right by Hsiao-Hung Pai [PDF]
, 2016 In Angry White People: Coming Face-to-Face with the British Far Right, the investigative journalist Hsiao-Hung Pai documents conversations and encounters with members of the English Defence League (EDL) and other key figures within the British far right,
Beresford, James
core