Results 71 to 80 of about 5,125,891 (281)
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
The Populist Revolt against Globalisation
Perspective Politice, 2017 A tormented wave of anti-establishment populism is haunting Europe. Populist parties have managed to enter the political centre stage. This is partly the result of the breakthrough of former extremeright or far right parties to the ‘regular right’ part ...
René CUPERUS
doaj
Researching Young People and Far-Right Populism
Social SciencesThis paper considers the challenges facing qualitative researchers who study far-right populism and youth. First, there is the question of the method itself.
Pam Nilan
doaj +1 more source
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Left-Wing Governments and Far-Right Success
British Journal of Political ScienceIn recent decades, support for the far right has surged in many countries. One common explanation for this is that far-right support is a backlash against left-wing governments and their policies.
Albert Falcó-Gimeno +2 more
doaj +1 more source
Molecular Oncology, EarlyView.We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source
Frontiers in Political ScienceThis study examines variation in far-right parties’ positions on the European Union (EU) by analytically distinguishing between radical and extreme-right actors and analysing their EU-related discourse.
Luca Mancin
doaj +1 more source
KEBANGKITAN POLITIK KANAN-JAUH DAN DAMPAKNYA BAGI MULTIKULTURALISME DI EROPA1
Dauliyah, 2017 Since 1970s the far right movement began to reappear in Europe. The emergence of the movement became an interesting phenomenon in Europe. This is because the history of the movement that affiliated with facism that leads to World War II.
Rizky Hikmawan
doaj +1 more source
, 2022 The coalition between Fratelli d’Italia, Lega, Forza Italia and some minor allies is expected to win the Italian general election on 25 September 2022 by a considerable margin, at least according to all the opinion polls.
Valerio Alfonso Bruno
core
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source