Results 61 to 70 of about 16,939,967 (257)
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
We further develop a recently introduced phase-field model of far-from-equilibrium alloy solidification under additive manufacturing conditions [K. Ji et al., Phys. Rev. Lett. 130, 026203 (2023)0031-900710.1103/PhysRevLett.130.026203].
Kaihua Ji, Mingwang Zhong, Alain Karma
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Paris on Stage: 1889-1914 [exhibition]; Cabaret de L’Enfer Model
Model of the facade of L'Enfer (Hell); Le Ciel (Heaven) is not shown, it was to the immediate left; A scale model, part of the Paris on Stage: 1889-1914 exhibition held June 19, 2013 to February 23, 2014.
unknown (Canadian model maker)
core
The small far infrared target of ship in surge interference is easy to have visual deviation causing the low accuracy of target positioning and the bad target identification performance.
Zhu Renping
doaj +1 more source
Precise fuel-air ratio (FAR) control on transient conditions is one of the key technologies for lean-burn spark-ignition (SI) engines. To improve fuel economy and reduce emissions, lean-burn engines must regulate their FAR immediately under different ...
Ping Wang, Chaojie Zhu, Jinwu Gao
doaj +1 more source
Liver organoids: modelling complexity in homeostasis and disease
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
June 1948. Map of Tokyo showing classes of roads, military routes, prinicipal streets, military installations, dependent houses and KU boundaries.; Index, mileage chart and insets on verso.; Also available online http://nla.gov.au/nla.map-vn4230572 ...
United States. Far East Command.
core
Epigenetic reprogramming of lineage switching in cancer
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Purpose: Physical activity on prescription (FaR) is a structured, evidence-based intervention aimed at increasing physical activity among patients through individualised prescriptions provided by healthcare professionals.
Maria Hagströmer, Ing-Mari Dohrn
doaj +1 more source

