Results 81 to 90 of about 27,102 (173)

A bottom-up approach to find lead compounds in expansive chemical spaces

open access: yesCommunications Chemistry
Drug discovery starts with the identification of a “hit” compound that, following a long and expensive optimization process, evolves into a drug candidate. Bigger screening collections increase the odds of finding more and better hits.
Álvaro Serrano-Morrás   +19 more
doaj   +1 more source

Tipificació de dos noms Cavanillesians, Galium Fruticescens (Rubiaceae) i Scorzonera pumila (Compositae) [PDF]

open access: yes, 2019
The Cavanillesian names Galium fruticescens and Scorzonera pumila, basionym of Launaea pumila, are lectotypified from original specimens preserved in the Cavanilles herbarium in the Royal Botanic Garden of Madrid (MA).Els noms cavanillesians Galium ...
Ferrer-Gallego, P. Pablo   +4 more
core  

Modulation of Tau Protein Neurotoxic Hallmarks by Novel σ1R Agonists/HDAC Inhibitor Dual‐Acting Compounds

open access: yesChemMedChem, Volume 21, Issue 5, 13 March 2026.
This study explores the development of dual‐acting compounds combining σ1R agonists and histone deacetylase inhibitors (HDACi). Key findings include compound 2d and 3a's high affinity for σ1R and favorable pharmacokinetic profile and an in vivo determined σ1R agonist profile by reversing the effect of the σ1R antagonist BD‐1063.
Antonino N. Fallica   +16 more
wiley   +1 more source

Annual Index [PDF]

open access: yesFarmacia Hospitalaria, 2016
Editor Jefe Farmacia Hospitalaria
doaj   +1 more source

La Farmacologia natural a l'obra de Fruitós Plans Pujol (1832-1890). [PDF]

open access: yes, 2017
L'objectiu que es pretén assolir és doble, d'una banda aprofundir en la biografia del catedràtic de la Facultat de Farmàcia de Barcelona Fruitós Plans Pujol, i aportar dades per tal d'anar completant-la, i, d'altra banda descriure la seva obra científica
Gaspar García, Ma. Dolores
core  

Annual Index [PDF]

open access: yesFarmacia Hospitalaria, 2015
Editor Jefe Farmacia Hospitalaria
doaj   +1 more source

Socio-environmental variables and transmission risk of lymphatic filariasis in central and northern Mozambique

open access: yesGeospatial Health, 2013
Lymphatic filariasis (LF) is endemic in Mozambique, where it is caused by Wuchereria bancrofti with Culex quinquefasciatus as the main vector. It affects approximately 10% of the population (2 million) with about 16 million at risk.
Isabel Manhenje   +2 more
doaj   +1 more source

Anàlisi dels indicadors de la gestió per processos de la docència pràctica a la Unitat de Laboratoris Docents (ULD) de la Facultat de Farmàcia [PDF]

open access: yes, 2014
[eng] In the Unitat de Laboratoris Docents (ULD) of the Faculty of Pharmacy a Quality System has been implemented to improve the management of the training laboratories and to introduce practical aspects of this system in the formation of the students ...
Benedí, Carles   +4 more
core  

Peer reviewers published in 2014 [PDF]

open access: yesFarmacia Hospitalaria, 2015
Editor Jefe Farmacia Hospitalaria
doaj   +1 more source

Flavonoids Affect Host-Microbiota Crosstalk through TLR Modulation

open access: yesAntioxidants, 2014
Interaction between host cells and microbes is known as crosstalk. Among other mechanisms, this takes place when certain molecules of the micro-organisms are recognized by the toll-like receptors (TLRs) in the body cells, mainly in the intestinal ...
Francisco J. Pérez-Cano   +3 more
doaj   +1 more source

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