Results 41 to 50 of about 21,895 (123)
Wee1 kinase differentially regulates maize CDKA2;1a and CDKB1;1
The FEBS Journal, EarlyView.In eukaryotes, Wee1 kinase inhibits the kinase activity of CDK/Cyc complexes through phosphorylation of a conserved residue in the CDK moiety. Wee1 is also present in plants, but has been scarcely studied. We have studied maize Wee1 regulation of CDKA/CycD2;2a or CDKB/CycD2;2a complexes.
Mingyar N. López‐Hernández +4 more
wiley +1 more source
Italian Patients Journey for Gene Therapy in Haemophilia A
Haemophilia, EarlyView.ABSTRACT Introduction Gene therapy (GT) provides sustained FVIII levels without repeated infusions in Hemophilia A (HA) patients thus overcoming a major limitation of replacement therapy. However, issues remain e.g., patient selection criteria, duration and variability of transgene expression, quality of life and long‐term safety.
Giovanni Di Minno +19 more
wiley +1 more source
Benign by design: A paradigm shift in cosmetic ingredient development
International Journal of Cosmetic Science, EarlyView.Benign by design strategies enable the creation of biodegradable cosmetic ingredients, reducing environmental persistence while maintaining the intended biological activity. This work compiles design rules and tools to guide the development of more sustainable molecules for the cosmetics industry.
Sandra Mota +3 more
wiley +1 more source
Journal of Animal Physiology and Animal Nutrition, EarlyView.ABSTRACT Microalgae such as Chlorella vulgaris are gaining attention as sustainable and nutritionally valuable feed ingredients, with the potential to partially replace soybean meal in broiler diets. However, dietary inclusion of 20% C. vulgaris has been attempted, but negatively affected growth performance due to limited digestibility.
Ana Rita Mendes +12 more
wiley +1 more source
Photochemistry and Photobiology, EarlyView.This study evaluated the photodegradation of commercial insect repellents containing DEET and IR‐3535 under UV‐A and UV‐B irradiation using Raman spectroscopy. Pure DEET and IR‐3535 showed intrinsic photostability, whereas DEET diluted in ethanol and a commercial DEET‐based formulation exhibited significant spectral changes after UV exposure.
Viviane Gadret Borio +4 more
wiley +1 more source
DST, 2001 As Doenças Sexualmente Transmissíveis vem se mantendo ao longo do tempo como problema de saúde pública. Após o surgimento da aids tal situação agravou-se.
Maria Elizabeth Ajalla +1 more
doaj
JACCP: JOURNAL OF THE AMERICAN COLLEGE OF CLINICAL PHARMACY, Volume 9, Issue 7, July 2026.ABSTRACT Background Pharmacist intervention (PI) is an important strategy for reducing drug‐related problems (DRP; events or circumstances related to drug therapy that actually or potentially interfere with desired health outcomes) and improving efficiency, quality, and clinical outcomes, thereby avoiding unnecessary health care costs.
Karine Dal Paz +2 more
wiley +1 more source
Pharmacoepidemiology and Drug Safety, Volume 35, Issue 7, July 2026.ABSTRACT Purpose To determine the trajectories of benzodiazepine (BZD) and Z‐drug use among older adults (n = 3590) followed in a network of geriatric outpatient clinics in Brazil. Methods This longitudinal study evaluated BZD and Z‐drug use over a 24‐month follow‐up period.
Nelson Machado do Carmo Júnior +5 more
wiley +1 more source
Memorias do Instituto Oswaldo Cruz, 2011 Biofilm production is an important mechanism that allows microbes to escape host defences and antimicrobial therapy. Vancomycin has been used largely for the treatment of methicillin-resistant staphylococcal infections.
Ana Lúcia Souza Antunes +6 more
doaj +1 more source
Influenza and Other Respiratory Viruses, Volume 20, Issue 7, July 2026.ABSTRACT Background Influenza causes 650,000 deaths, 3–5 million hospitalizations, and 1 billion cases worldwide each year. There is a limited repertoire of antivirals available to tackle this burden, highlighting the risk of developing resistance to current drugs.
Alejandro Martín‐Toribio +15 more
wiley +1 more source