Results 61 to 70 of about 125,996 (160)
In our study, we obtained both non‐covalent and covalent PLpro inhibitors. Additionally, the stable protein‐ligand interactions of the active compound were examined using advanced computational docking and molecular dynamics simulations. The non‐covalent inhibitor 2t showed antiviral activity with an EC50 of 2.89 µM, indicating its potential as a ...
Elena‐Oriana Iuga +11 more
wiley +1 more source
As Doenças Sexualmente Transmissíveis vem se mantendo ao longo do tempo como problema de saúde pública. Após o surgimento da aids tal situação agravou-se.
Maria Elizabeth Ajalla +1 more
doaj
Síndrome metabólica e risco cardiovascular [PDF]
Sumário pormenorizado da lição apresentado para provas de agregação em Farmácia, na especialidade de Farmacologia e Farmacoterapia, da Faculdade de Farmácia da Universidade de ...
Pereira, Isabel Vitória Neves de Figueiredo Santos
core
Exploring 6‐Hydroxy‐3‐Aryl/Heteroarylcoumarins as Promising Candidates Against Trypanosoma cruzi
New therapies are urgently needed for Chagas disease, and screening of 6‐hydroxy‐3‐aryl/heteroarylcoumarin derivatives identified highly selective compounds with potent activity against T. cruzi. In particular, derivative 1f showed submicromolar trypomastigote potency, dual‐stage activity, and inhibition of amastigote‐to‐trypomastigote differentiation,
C. N. Pereira +7 more
wiley +1 more source
Biofilm production is an important mechanism that allows microbes to escape host defences and antimicrobial therapy. Vancomycin has been used largely for the treatment of methicillin-resistant staphylococcal infections.
Ana Lúcia Souza Antunes +6 more
doaj +1 more source
Ambiente virtual para treino de competências de comunicação na área da saúde : o caso do atendimento em farmácia para automedicação [PDF]
Este artigo descreve um protótipo de Realidade Virtual destinado ao treino de competências técnicas e de comunicação dos estudantes de Ciências Farmacêuticas. Numa situação simulada, um humano virtual desempenha o papel de um paciente/doente que requer o
Carmo, Maria Beatriz +6 more
core
Beyond Water: Deep Eutectic Solvents Enable Dye‐Sensitised Photocatalytic Hydrogen Production
Dye‐sensitised photocatalytic H2 evolution is demonstrated for the first time in deep eutectic solvents (DESs). Carbazole‐based dyes with different hydrophobicity sensitise Pt@TiO2, revealing that heterogeneous dye–DES combinations maximise activity. Interfacial solvation and charge transfer govern enhanced hydrogen production under visible light. This
Chiara L. Boldrini +8 more
wiley +1 more source
Heterogeneous‐catalyzed selective and versatile hydrogenative functionalizations of phthalimides have been developed for the first time. By using a solid nanocomposite formed by [Ag/Al2O3] material in combination with [H‐BETA] zeolite as cocatalyst, a broad range of 3‐functionalized isoindolinones have been accesed in one‐pot from phthalimides, H2 and ...
Carles Lluna‐Galán +2 more
wiley +1 more source
This study shows that the beneficial effect of Nb by Ti partial substitution on TiO2 consists of a significant increase in the lithium diffusion coefficient, resulting from the opening of structural tunnels. This explains the intercalation pseudocapacitive behavior of Nb‐derivatives of TiO2. The electrochemical performance of a rutile with high niobium
Andrés Solana +2 more
wiley +1 more source

