Results 51 to 60 of about 1,637 (189)

Estrategias de negocios de las farmacias del municipio Maracaibo

Telos: Revista de Estudios Interdisciplinarios en Ciencias Sociales, 2008
El propósito fundamental de este estudio fue analizar las estrategias de negocios aplicadas por las farmacias ubicadas en el municipio Maracaibo, bajo los preceptos teóricos de Thompson y Strickland (2003) y Villalba (2000).
Giancarlo Salazar, Wileidys Artigas
doaj  

Investigating enzyme function by geometric matching of catalytic motifs

Protein Science, Volume 35, Issue 9, September 2026.
Abstract The rapidly growing universe of predicted protein structures offers opportunities for data driven exploration but requires computationally scalable and interpretable tools. We developed a method to detect catalytic features in protein structures, providing insights into enzyme function and mechanism.
Raymund E. Hackett, Ioannis G. Riziotis, Martin Larralde, António J. M. Ribeiro, Georg Zeller, Janet M. Thornton   +5 more
wiley   +1 more source

Key Strategies for Improving Psychiatric Home‐Based Care in Spain: A Modified Delphi Study

Scandinavian Journal of Caring Sciences, Volume 40, Issue 3, September 2026.
ABSTRACT Aims This study aimed to identify and prioritize key strategies for improving a psychiatric home‐based care programme, the Crisis Resolution and Home Treatment (CRHT) intervention in Catalonia, Spain. The objective was to incorporate the perspectives of service users, family caregivers and healthcare professionals to guide quality improvement ...
Ana María Besoaín‐Cornejo, Montserrat Gil‐Girbau, Luisa Baladón Higueras, Cristina Pou Matarranz, Maria Rubio‐Valera   +4 more
wiley   +1 more source

Topliss‐Guided Optimization of Acetanilide‐Based Soluble Epoxide Hydrolase Inhibitors: Exploring the Pentafluorosulfanyl Group as a Potency‐Enhancing Motif

ChemMedChem, Volume 21, Issue 16, 27 August 2026.
Can an amide analog retain the high potency of the classic urea motif in soluble epoxide hydrolase inhibitors? Through a single unconventional switch, the introduction of the underexplored pentafluorosulfanyl group into an amide analog of TPPU, the authors restored high inhibitory potency.
Alba López‐Ruiz, Eugènia Pujol, Cristian Ramos, Valeria Rizzo, Christophe Morisseau, Cristina Val, Tiziana Ginex, Javier Vázquez, Sandra Codony, Andreea L. Turcu, Belén Pérez, Elena Sáez, Antonio Pineda‐Lucena, Bruce D. Hammock, F. Javier Luque, M. Isabel Loza, José Brea, Santiago Vázquez   +17 more
wiley   +1 more source

Noninnocent Deep Eutectic Solvents Enable Selective, Sustainable Nickel‐Catalyzed Cross‐Electrophile Couplings to Diarylmethanes

ChemSusChem, Volume 19, Issue 16, 27 August 2026.
Ni‐catalyzed cross‐electrophile coupling (XEC) of aryl iodides with benzyl chlorides proceeds efficiently in the deep eutectic solvent (DES) choline chloride/urea, replacing hazardous amide solvents. Under mild, aerobic, heterogeneous conditions, diarylmethanes form in up to 95% yield.
Andrea Nicola Paparella, Maristella Simone, Alessia Battezzato, Laura Chevet, Laetitia Chausset‐Boissarie, Muriel Durandetti, Filippo Maria Perna, Vito Capriati   +7 more
wiley   +1 more source

Underexplored Ligand‐Binding Features of FabI From Staphylococcus aureus and Escherichia coli: A Comparative Pharmacophoric Modeling and Surface Mapping Approach

ChemMedChem, Volume 21, Issue 15, 14 August 2026.
Antimicrobial resistance highlights the urgent need for novel FabI inhibitors. Using an integrated computational approach combining ConPhar pharmacophore modeling, FTMap surface mapping, and PLIP interaction profiling across experimental structures and structures from MD simulations, we identified a conserved binding core (Y156/Y157, A95) and ...
Pedro Tenório T. F. Leite, Lucas H. S. Ocarino, Gabriel C. Veríssimo, Philipe O. Fernandes, Dara Fernanda Pereira, Fernanda Kelly M. e Oliveira, Alberto Marbán‐González, José L. Medina‐Franco, Mateus Sá M. Serafim, Thales Kronenberger, Vinícius G. Maltarollo   +10 more
wiley   +1 more source

Análisis de la demanda de antibióticos en farmacia comunitaria con receta privada, prescripción irregular y sin receta (automedicación): perfil de las farmacias y los farmacéuticos comunitarios participantes

Farmacéuticos Comunitarios, 2018
Introducción: La resistencia a los antibióticos constituye uno de los mayores desafíos que afronta la medicina en la actualidad. Es una amenaza creciente para la salud pública que afecta a todos los países del mundo debido a que los nuevos mecanismos de ...
Molinero A, Carbajal de-Lara JA, Cantalapiedra Fernández F, Eguilleor Villena A, Gutiérrez Ríos P   +4 more
doaj   +1 more source

Biobased Polyurethane Films Based on Andiroba (Carapa guianensis) and Buriti (Mauritia flexuosa) Oil Polyols

Journal of Applied Polymer Science, Volume 143, Issue 30, August 10, 2026.
Polyurethane films were prepared from andiroba (Carapa guianensis) and buriti (Mauritia flexuosa) oil‐derived polyols, emphasizing their potential as bio‐based materials. UV–Vis analysis indicates the retention of carotenoid‐related chromophoric features within the polymer matrix.
João A. P. da Silva, Amanda L. Ferreira, Felipe F. C. Tavares, Chana M. da Silva, Cesar L. Petzhold, Nilo S. M. Cardozo   +5 more
wiley   +1 more source

APOE and genetic risk variants influence Alzheimer's disease onset in carriers of an extra copy of APP, with and without Down syndrome

Alzheimer's &Dementia, Volume 22, Issue 8, August 2026.
Abstract INTRODUCTION An extra copy of the amyloid precursor protein (APP) gene causes autosomal dominant Alzheimer's disease (AD) and AD in Down syndrome (DS), but the factors underlying variability in age at onset (AAO) remain unclear. We investigated whether sporadic AD risk variants modify AAO. METHODS We analyzed clinical and genetic data from 100
Joan Groeneveld, Danna Perlaza, Clàudia Olivé, Lou Grangeon, Niccolo Tesi, Aude Nicolas, Chenyang Jiang, Itziar de Rojas, David Wallon, Stéphane Rousseau, Marta Rovira, Diego Real de Asúa, Fernando Moldenhauer, Ruihao Mu, Kévin Cassinari, Aline Zarea, Joaquim Aumatell Escabias, Jean‐Charles Lambert, Yolande A. L. Pijnenburg, Marc Hulsman, Everard G. B. Vijverberg, Johannes Levin, Mathias Jucker, Eric McDade, Juan Fortea, Henne Holstege, Flora H. Duits, Lisa Vermunt, Maulikkumar Patel, Matthew Johnson, Alan E. Renton, Alison M. Goate, Carlos Cruchaga, Cyril Pottier, Maria Victoria Fernandez, Olivia Belbin, Gael Nicolas, Oriol Dols‐Icardo, Sven J. van der Lee, Dominantly Inherited Alzheimer Network   +39 more
wiley   +1 more source

Farmacia comunitaria y oficina de farmacia [editorial]

Farmacéuticos Comunitarios, 2012
Durante la mayor parte de la historia de nuestra profesión la función del farmacéutico se relacionó con la elaboración de los medicamentos. La Farmacia se separó de la Medicina porque la sociedad necesitaba un especialista conocedor de los elementos disponibles en la naturaleza para el alivio o curación de los males que ponían en peligro la salud de ...
openaire   +1 more source