Results 11 to 20 of about 5,697 (131)

Farmacocinética de los anticuerpos monoclonales [PDF]

, 2021
Los anticuerpos monoclonales (mAb) representan uno de los grupos terapéuticos de mayor interés en el desarrollo farmacológico. Por toda su complejidad (estructural y funcional), el seguimiento farmacocinético de los fármacos biológicos debería ser ...
Casellas Gibert, M., Padullés Zamora, Ariadna, Colom Codina, Helena, Padullés Zamora, Núria, Santacana Juncosa, Eugènia   +4 more
core   +5 more sources

Noncompartmental pharmacokinetics of three intravenous mycophenolate mofetil concentrations in healthy Standardbred mares

Veterinary Dermatology, Volume 34, Issue 3, Page 222-234, June 2023., 2023
Background – Mycophenolate mofetil (MMF) is the prodrug of mycophenolic acid (MPA) which acts as an immunosuppressive agent. During the biotransformation of MMF to MPA, additional metabolites including MPA phenol glucuronide (MPAG), MPA acyl glucuronide (AcMPAG) and MPA phenol glucoside (MPG) are formed.
Dylan L. Burroughs, Gwendolen Lorch, Yizhen Guo, Kasey Hill, Eric L. Schroeder, Lynette K. Cole, Mitch A. Phelps   +6 more
wiley   +1 more source

FARMACOCINÉTICA DAS ISOFLAVONAS DA SOJA [PDF]

, 2010
As isoflavonas são fitoestrógenos que estão presentes em determinados alimentos, como a soja e seus derivados. Essas substâncias podem gerar muitos efeitos benéficos à saúde humana, sendo assim consideradas um alimento nutracêutico.
Mendel, Monique Theissen, Suyenaga, Edna Sayuri   +1 more
core   +2 more sources

PI‐07: THE INTERNATIONAL HEMOGLOBINOPATHY RESEARCH NETWORK (INHERENT): AN INTERNATIONAL INITIATVE TO STUDY THE ROLE OF GENETIC MODIFIERS IN HEMOGLOBINOPATHIES

, 2022
HemaSphere, Volume 6, Issue S4, Page 12-13, August 2022.
KOUNTOURIS P., STEPHANOU C., ARCHER N., BONIFAZI F., GIANNUZZI V., KUO K., MAGGIO A., MAKANI J., MAÑÚ PEREIRA M., MICHAILIDOU K., NKYA S., NNODU O., TROMPETER S., TSHILOLO L., WONKAM A., ZILFALIL B., INUSA B., KLEANTHOUS M.   +17 more
wiley   +1 more source

Potential Pharmacokinetic Drug‐Drug Interactions between Cannabinoids and Drugs Used for Chronic Pain

BioMed Research International, Volume 2020, Issue 1, 2020., 2020
Choosing an appropriate treatment for chronic pain remains problematic, and despite the available medication for its treatment, still, many patients complain about pain and appeal to the use of cannabis derivatives for pain control. However, few data have been provided to clinicians about the pharmacokinetic drug‐drug interactions of cannabinoids with ...
Marta Vázquez, Natalia Guevara, Cecilia Maldonado, Paulo Cáceres Guido, Paula Schaiquevich, Eiichi Kumamoto   +5 more
wiley   +1 more source

A Population Pharmacokinetic Approach to Describe Cephalexin Disposition in Adult and Aged Dogs

Veterinary Medicine International, Volume 2014, Issue 1, 2014., 2014
This study was conducted in order to characterize the pharmacokinetics of orally administered cephalexin to healthy adult and aged dogs, using a population pharmacokinetic approach. Two hundred and eighty‐six cephalexin plasma concentrations obtained from previous pharmacokinetic studies were used.
Ana Paula Prados, Paula Schaiquevich, Verónica Kreil, Agustina Monfrinotti, Pamela Quaine, Lisa Tarragona, Ruben Hallu, Marcela Rebuelto, Guillermo Virkel   +8 more
wiley   +1 more source

Plasma and Ocular Prednisolone Disposition after Oral Treatment in Cats

BioMed Research International, Volume 2013, Issue 1, 2013., 2013
Objective. To evaluate the plasma and aqueous humor disposition of prednisolone after oral administration in cats. Methods. Six cats were administered with a single oral dose of prednisolone (10 mg). Blood and aqueous humor samples were serially collected after drug administration.
María J. Del Sole, Paula Schaiquevich, Marcelo A. Aba, Carlos E. Lanusse, Laura Moreno, Robert J. Lee   +5 more
wiley   +1 more source

Farmacocinética Clínica [PDF]

, 1997
Los servicios de Farmacocinética Clínica se desarrollaron en los hospitales de Estados Unidos por la década de los años sesenta, como consecuencia del auge de la biofarmacia y farmacocinética en los centros universitarios.
González Marín, Guillermo
core   +1 more source

The 4th Global Congress on Sickle Cell Disease Abstract Book 2022

, 2022
HemaSphere, Volume 6, Issue S4, Page 1-64, August 2022.
wiley   +1 more source

Determination of Ranitidine in Human Plasma by SPE and ESI‐LC‐MS/MS for Use in Bioequivalence Studies

International Scholarly Research Notices, Volume 2013, Issue 1, 2013., 2013
A method for determining ranitidine in human plasma by ESI‐LC‐MS/MS was validated, using propranolol as internal standard. The extraction method used was solid phase extraction (SPE). Chromatographic separation was performed in a Chromolith C18 (50 mm × 4.6 mm i.d.) analytical column, which provided good separation of ranitidine and propranolol peaks ...
Karini B. Bellorio, Maria Isabel R. Alves, Nelson R. Antoniosi Filho, J.-F. Jen, J. Millership, A. Sanches Silva   +5 more
wiley   +1 more source