Results 11 to 20 of about 2,735 (147)

Visual rating of the medial temporal lobe atrophy on magnetic resonance imaging in elderly patients with type I bipolar disorder [PDF]

Alzheimers Dement
Abstract Background Bipolar disorder (BD) is associated with cognitive impairments and structural brain changes, including brain atrophy. This study aims to evaluate medial temporal lobe atrophy (MTA) – through the visual evaluation of hippocampus, choroid fissure, and temporal horn – in elderly individuals with type‐I bipolar BD on magnetic resonance ...
Ladeira R, Leduc V, Radanovic M, Duran F, Vallada H, Forlenza O.   +5 more
europepmc   +2 more sources

Ten‐year course of treated bipolar I disorder: The role of polarity at onset

Brain and Behavior, Volume 11, Issue 11, November 2021., 2021
Abstract Introduction Early‐stage predictors of illness course are needed in bipolar disorder (BD). Differences among patients with a first depressive versus maniac/hypomanic episode have been stated, although in most studies, memory bias and time from onset to start of specialized treatment might interfere. The aim was to compare the first 10 years of
María Yoldi‐Negrete, Ana Fresán‐Orellana, Mariana Jiménez‐Tirado, Sara Martínez‐Camarillo, Lino Palacios‐Cruz, Eduard Vieta, Hiram Ortega‐Ortiz, Claudia Becerra‐Palars, Doris Gutiérrez‐Mora, Beatriz Camarena Medellín   +9 more
wiley   +1 more source

Pharmacogenetics, tobacco, alcohol and its effect on the risk development cancer [PDF]

, 2018
Indexación: Scopus; Scielo.Cancer is the second leading cause of death in the world, causing 8.8 million deaths in 2015 according to the World Health Organization (WHO). Risk factors for cancer include smoking and alcohol consumption.
Acevedo, C., Cayún, J.P., Cerda, B., Cerro, R., Cáceres, D., Lavanderos, A., Quiñones, L.A., Roco, Á., Rubilar, J.C., Varela, N.   +9 more
core   +1 more source

Toward a clinical practice guide in pharmacogenomics testing for functional polymorphisms of drug-metabolizing enzymes. Gene/drug pairs and barriers perceived in Spain [PDF]

, 2012
The development of clinica lpractice recommendations or guidelines for the clinical use of biomarkers is an issue of great importance withr regard to adverse drug reactions.The poten-tial of pharmacogenomicbiomarkers has been extensively investigated in
Abad Santos, Francisco, Aldea, Ana, Alonso-Navarro, Hortensia, Bernal, María Luisa, Borobia, Alberto M., Borràs, Emma, Carballo, Miguel, Carvajal, Alfonso, García-Agúndez, José Augusto, García-Martín, Elena, García-Muñiz, José D., Gervasini, Guillermo, Jiménez-Jiménez, Félix Javier, Lucena, María Isabel, Martínez, Carmen, Sacristán, José A., Salado, Inés, Sinués, Blanca, Vicente, Jorge   +18 more
core   +4 more sources

Polimorfismo de proteína 5,10-metilentetrahidrofolato reductasa en población venezolana

Revista Digital de Postgrado, 2023
El folato es un miembro del grupo de la vitamina B y está relacionado con enfermedades crónicas como anemia megaloblástica, enfermedad cardiovascular, cáncer, disfunción cognitiva y riesgo de defectos del tubo neural.
Mary Carmen Chacin, Martha Bravo, Anabel Arends   +2 more
doaj   +1 more source

Clinical applications of pharmacogenomics [PDF]

, 2017
Indexación: Scopus.Pharmacogenomics is an emergent field aimed at tailoring pharmacological therapy. Genetic polymorphisms can modify the expression and function of enzymes and proteins involved in drug metabolism, affecting absorption, distribution ...
Cayún, J.P., Escalante, P., Gallegos, B., Lares-Asseff, I., Meneses, F., Miranda, C., Quiñones, L., Roco, Á., Varela, N., Zaruma-Torres, F.   +9 more
core   +1 more source

Characterization of LDLR rs5925 and PCSK9 rs505151 genetic variants frequencies in healthy subjects from northern Chile: Influence on plasma lipid levels

Journal of Clinical Laboratory Analysis, Volume 33, Issue 9, November 2019., 2019
Abstract Background Identification and characterization of genetic variants and their effects on human health may allow to establish relationships between genetic background and susceptibility to developing cardiovascular diseases. LDLR and PCSK9 polymorphisms have been associated with higher lipid levels and risk of cardiovascular diseases.
Claudio Rojas, Hugo Ramírez, Luis A. Salazar, Alexis M. Kalergis, Anita S. Gálvez, Jorge Escobar‐Vera   +5 more
wiley   +1 more source

Convierte tu sueño profesional en realidad en el octavo congreso de SEFAC en Alicante [PDF]

, 2018
“Haz de tu vida un sueño y de tu sueño una realidad”. Esta perla de sabiduría del autor de El principito, Antonie de Saint-Exupéry, refleja como pocas el genio de todos aquellos  pioneros que fueron capaces de transformar su presente anticipándose al ...
Climent Catalá, Maite, Prats Mas, Rosa
core   +2 more sources

NESTED-PCR VS RT-QPCR: UMA COMPARAÇÃO DA SENSIBILIDADE NA DETECÇÃO DE ALTERAÇÕES GENÉTICAS EM PACIENTES COM LEUCEMIAS AGUDAS

Hematology, Transfusion and Cell Therapy, 2023
Objetivo: Diante da importância da detecção de alterações genéticas em pacientes com leucemias, o objetivo desse estudo foi comparar a sensibilidade das técnicas Nested -PCR e RT-qPCR na detecção de alterações genéticas em pacientes portadores de ...
FMCP Pessoa, IV Barreto, RB Gadelha, CB Machado, BMD Nogueira, AKC Machado, RM Ribeiro, MEA Moraes, MOM Filho, CA Moreira-Nunes   +9 more
doaj   +1 more source

FARMACOGENÉTICA APLICADA AO CÂNCER. QUIMIOTERAPIA INDIVIDUALIZADA E ESPECIFICIDADE MOLECULAR

Medicina, 2006
A farmacogenética estuda a correlação entre variações genéticas e a resposta aos fármacos. Essa abordagem tem apelo especial para a oncologia visto que a quimioterapia do câncer é certamente a modalidade terapêutica em que mais se convive com uma elevada
Marcelo Reis
doaj   +1 more source