Results 31 to 40 of about 50,623 (163)

Thrombospondin‐4 is upregulated in abdominal aortic aneurysm: A vasoprotective response with potential therapeutic relevance

British Journal of Pharmacology, EarlyView.
TSP4 is upregulated in human and experimental AAA. TSP4 knockdown accelerated AAA formation and exacerbated both vascular inflammation and remodelling, emphasizing that TSP4 upregulation may represent a protective response against AAA. Our findings suggest that preserving TSP4 could be a useful strategy in the clinical management of AAA.
Laia Blanco‐Casoliva, Lidia Puertas‐Umbert, Judith Alonso, Rafael Almendra‐Pegueros, Saray Varona, Mercedes Camacho, Gemma Arderiu, Lluís Asmarats, Marta Alegret, Jose Martinez‐Gonzalez, Cristina Rodriguez   +10 more
wiley   +1 more source

¿Se acerca el fin de la succinilcolina? Estudio dosis-respuesta de Sugammadex

Revista Electrónica de AnestesiaR, 2009
En un estudio preliminar en 10 voluntarios sanos se vio que Sugammadex era capaz de revertir en 2 minutos una dosis de 0,6mg/kg de rocuronio administrada 3 minutos antes.
Miguel Miró
doaj   +1 more source

Air exposure test in Colossoma macropomum juveniles maintained in water at suboptimal temperature: Physiological, metabolic and oxidative stress responses

Journal of Fish Biology, EarlyView.
Abstract This study evaluated the physiological, metabolic and oxidative responses of Colossoma macropomum subjected to air exposure when maintained in water at suboptimal temperature (23°C). A total of 54 fish (81.33 ± 11.90 g) were distributed into nine tanks (6 fish per tank). For the air exposure test, 24 animals were exposed for 30 min and another
Gisele Cristina Favero, Luanna do Carmo Neves, Suzane Lilian Beier, Hugo Napoleão Pereira da Silva, Juan Lameira Dornelles, Bernardo Baldisserotto, Glauber David Almeida Palheta, Nuno Filipe Alves Correia de Melo, Ronald Kennedy Luz   +8 more
wiley   +1 more source

Efectos de la administración crónica de carvedilol sobre la variabilidad de la presión arterial y el daño de órgano blanco en ratas con desnervación sinoaórtica [PDF]

, 2015
Background: Increased blood pressure variability is a novel risk factor for the development of target organ injury both in hypertensive and normotensive subjects, so its reduction should be considered as a new therapeutic goal. Objective: The aim of this
Bertera, Facundo Martin, Carranza, Maria Andrea, del Mauro, Julieta Sofía, Donato, Pablo Martín, Gelpi, Ricardo Jorge, Gorzalczany, Susana Beatriz, Höcht, Christian, Santander Plantamura, Yanina Alejandra, Taira, Carlos Alberto   +8 more
core  

Modulation of c-Jun NH2-Terminal (JNK) by Cholinergic Autoantibodies from Patients with Sjögren’s Syndrome [PDF]

, 2011
Background: We wanted to determine (via an immunopharmacological approach) whether the c-Jun NH2 terminal kinase (JNK) cascade is phosphorylated in the submandibular gland by carbachol and cholinergic autoantibodies (IgG) present in the sera of patients ...
Borda, Enri Santiago, Passafaro, Daniela, Reina, Silvia, Sterin Borda, Leonor   +3 more
core   +1 more source

Evaluating Leadership and Teamwork Competency Acquisition Through Clinical Simulation: Development of the Clinical Simulation Learning Leadership and Teamwork Scale

Journal of Clinical Nursing, EarlyView.
ABSTRACT Advanced simulation is a methodology that allows the development of technical skills and transversal skills such as teamwork and leadership. There are tools to measure the development of technical competencies and student satisfaction with the methodology, but not to measure the development and use of transversal competencies in the clinical ...
Rafael González‐Moret, Beatriz Rodríguez Díez‐Caballero, Manuel Romero‐Saldaña, Daniel García‐Gutiérrez, Cristina García‐Salido, Estel·la Ramírez‐Baraldes, Isabel Serra Guillén   +6 more
wiley   +1 more source

Evaluación profesoral del proceso enseñanza-aprendizaje de la disciplina de Farmacología en una universidad angolana.

Revista Española de Educación Médica
Antecedentes: La disciplina de Farmacología se imparte en el quinto y sexto semestre con una carga de 64 horas respectivamente en la carrera universitaria de licenciatura en ciencias farmacéuticas en el Instituto Superior Politécnico Jean Piaget de ...
Fernando Bange Cassenda Fernando, Ana Fernandes, Agostinho Chipango, Roberto Lardoeyt Ferrer   +3 more
doaj   +1 more source

Myoclonus induced by salbutamol: A case report

Biomédica: revista del Instituto Nacional de Salud, 2018
Salbutamol is a β2 adrenergic agonist widely prescribed in patients with obstructive and restrictive lung diseases. The main side effects associated with its use are tachycardia and tremor. Myoclonus is an involuntary, irregular, abrupt, brief and sudden
María Alejandra Montoya-Giraldo, Dayana Vanessa Montoya, David Alexander Atehortúa, Jefferson Antonio Buendía, Andrés Felipe Zuluaga   +4 more
doaj   +1 more source

Toward a clinical practice guide in pharmacogenomics testing for functional polymorphisms of drug-metabolizing enzymes. Gene/drug pairs and barriers perceived in Spain [PDF]

, 2012
The development of clinica lpractice recommendations or guidelines for the clinical use of biomarkers is an issue of great importance withr regard to adverse drug reactions.The poten-tial of pharmacogenomicbiomarkers has been extensively investigated in
Abad Santos, Francisco, Aldea, Ana, Alonso-Navarro, Hortensia, Bernal, María Luisa, Borobia, Alberto M., Borràs, Emma, Carballo, Miguel, Carvajal, Alfonso, García-Agúndez, José Augusto, García-Martín, Elena, García-Muñiz, José D., Gervasini, Guillermo, Jiménez-Jiménez, Félix Javier, Lucena, María Isabel, Martínez, Carmen, Sacristán, José A., Salado, Inés, Sinués, Blanca, Vicente, Jorge   +18 more
core   +4 more sources

Hair Cortisol Concentrations in Children: A Longitudinal Analysis Across Childhood

Developmental Psychobiology, Volume 68, Issue 3, May 2026.
ABSTRACT Hair cortisol concentration (HCC) reflects long‐term cortisol exposure and is commonly used as a biomarker of hypothalamic–pituitary–adrenal axis activity. Although increasingly applied in pediatric populations, developmental changes in HCC and potential sex differences remain unclear.
Miguel Ángel Baos‐González, Javier De Echarri‐Lorente, María Ángeles García‐León, Raquel González‐Pérez, María Isabel Peralta‐Ramírez   +4 more
wiley   +1 more source