Results 61 to 70 of about 51,442 (210)

Microbial Chemical Diversity and Cytotoxic Potential From Brazilian Ferruginous Caves: A Pioneering Metabolomic Survey

open access: yesChemistry &Biodiversity, Volume 23, Issue 1, January 2026.
ABSTRACT Cave microbiomes represent a rich yet understudied source of chemical diversity with biotechnological properties. Microorganisms in these environments thrive under extreme conditions such as darkness, oligotrophy, and high concentrations of inorganic matter like iron ore.
Natália Naomi Kato   +5 more
wiley   +1 more source

Synthesis of Benzopyrans and Quinolines with Nitrogenated Chain and Their Cytotoxicity Against Human Cancer Cell Lines

open access: yesChemMedChem, Volume 21, Issue 2, January 2026.
Natural products and/or their structural analogs represent the greatest number of approved small‐molecules as antitumor agents. We report the synthesis of 2‐propanamide and 2‐propanamine dihydrobenzopyrans and 2‐ and 2,3‐disubstituted quinolines to evaluate their cytotoxicity against human A549 (lung), A2058 (melanoma), HepG2 (liver), MCF‐7 (breast ...
Bernabeu‐Sanchis Álvaro   +8 more
wiley   +1 more source

Methodological proposal with an interdisciplinary approach for teaching learning content theory of the pharmacological receptor in the medical career

open access: yesMedisur, 2021
Background: in therapeutic decision-making, the importance of knowledge of the drug receptor theory content is recognized; however, there is a lack of proposals from interdisciplinarity, which is useful as reference for teachers to improve the teaching ...
Yeny Dueñas Pérez   +5 more
doaj  

Therapeutic Perspectives of SIRT6 Regulation: Computational Analysis of Activation and Inhibition by Bioactive Molecules

open access: yesJournal of Molecular Recognition, Volume 39, Issue 1, January 2026.
ABSTRACT Sirtuin 6 (SIRT6) is an enzyme belonging to the class of nicotinamide adenine dinucleotide (NAD+) dependent histone deacetylases. It has been of interest due to its multivariate biological role and association with aging‐related diseases and metabolic dysfunctions.
Érika Geicianny de Carvalho Matias   +5 more
wiley   +1 more source

ICB digital [PDF]

open access: yes
A partir del núm. 91 es diu: ICB digital.
Sociedad Española de Farmacología Clínica
core  

SYNTESIS AND CRYSTALLINE STRUCTURE OF THE EXO-3,6-DIMETHYL-3,6-EPOXI-1,2,3,6-TETRAHYDROPHTLALIMIDE AND ITS N-BROMODECYL ANALOG: TWO THERMALLY LABILE DIELS-ALDER ADDUCTS [PDF]

open access: yes, 2014
Indexación: Web of Science; Scielo.The molecular structure of the exo-3,6-dimethyl-3,6-epoxi-1,2,3,6-tetrahydrophthalimide (1), determined by X-ray diffraction analysis, as well as, its complete spectroscopic characterization and the synthesis and ...
ARAYA-FUENTES, EYLEEN   +4 more
core   +2 more sources

FARMACOLOGÍA AVIAR 1ª PARTE: PRINCIPIOS BÁSICOS SOBRE LA ADMINISTRACIÓN DE FÁRMACOS ANTIINFECCIOSOS EN AVICULTURA

open access: yesRevista de la Facultad de Medicina Veterinaria y de Zootecnia, 2005
El presente artículo es una revisión sobre los principios básicos de los fármacos antiinfec¬ciosos utilizados en la avicultura. Se discuten las indicaciones de los fármacos, sus dosis y vías de administración.
Sánchez G.
doaj   +2 more sources

Contribución de los receptores nicotícos a la neuroprotección y a la neuroinflamación [PDF]

open access: yes, 2014
Tesis doctoral inédita leída en la Universidad Autónoma de Madrid. Facultad de Medicina. Departamento de Farmacología y Terapéutica.
Parada Pérez, Esther
core   +1 more source

CONSIDERACIONES FARMACOLÓGICAS GENERALES Y PARTICULARES EN CUIDADOS INTENSIVOS

open access: yesRevista Médica Clínica Las Condes, 2016
La correcta administración de medicamentos en el paciente crítico constituye un desafío permanente para los equipos de cuidados intensivos. Esto está determinado por factores propios del paciente, como lo son sus profundos cambios metabólicos y ...
Dr. Tomás Regueira, PhD.
doaj   +1 more source

Signal transduction mechanism of biased ligands at histamine H2 receptors [PDF]

open access: yes, 2014
7TMRs (seven-transmembrane receptors) exist as conformational collections in which different conformations would lead to differential downstream behaviours such as receptor phosphorylation, G-protein activation and receptor internalization.
Alonso, Natalia   +5 more
core   +1 more source

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