Results 51 to 60 of about 1,276 (175)

Effect of Linaclotide on Colonic Motility Assessed With Intraluminal Colonic High‐Resolution Manometry in Healthy Subjects. An Acute, Open Label, Randomized, Crossover, Reader‐Blinded Study

Neurogastroenterology &Motility, EarlyView.
Our study showed that, in healthy controls, acute administration of linaclotide increased the total number of long‐distance propagating and the pre‐prandial pancolonic pressurizations. Further studies need to address whether the observed effects are directly or indirectly mediated by the mechanism of action of this useful medication to treat chronic ...
Christian Lambiase, Giuseppe Pagliaro, Silvia Cocca, Eveline Deloose, Ingrid Demedts, Riccardo Morganti, Jan Tack, Maura Corsetti   +7 more
wiley   +1 more source

Anticipatory, Chronic, and Imminent: A Typology of Insecurities Underlying Protracted Conflict Displacement and Its Implications

Population and Development Review, EarlyView.
Abstract Protracted armed conflicts increasingly drive long‐term displacement, yet demographic frameworks often treat forced migration from conflict settings as a response to acute, singular events. This study introduces a typology of displacement grounded in the tempo and form of conflict‐related insecurities—anticipatory, chronic, and imminent—and ...
Stephanie M. Koning, Goleen Samari, Abigail Weitzman   +2 more
wiley   +1 more source

Employing a Hysteresis Approach to Analyze Shifts in Tree Physiological Thresholds in Response to Drought

Plant, Cell &Environment, EarlyView.
ABSTRACT Drought‐induced tree mortality underscores the need for improved physiological models to predict tree responses to water stress. We employed a hysteresis modelling approach analyzing diel water absorption and desorption cycles to understand drought‐induced shifts in physiological thresholds.
Mauro Brum, Annie Deslauriers, Matthew Vadeboncoeur, Tanner Frost, David Moore, Caroline Rodrigues da Silva, Daniel B. Metcalfe, Heidi Asbjornsen   +7 more
wiley   +1 more source

Safeguarding Merit: Citizen Support for Civil Service Protections Against Political Interference

Public Administration Review, EarlyView.
ABSTRACT President Trump altered the U.S. federal civil service system by reducing merit‐based protections for bureaucratic expertise and expanding the scope of political appointments, shifting the balance long established under the Pendleton Act of 1883. Similar reforms have occurred at the state level with moves to at‐will employment.
Colt Jensen, Jaclyn Piatak
wiley   +1 more source

Korat‐Scrub Typhus Score: A Clinical Tool for Predicting Scrub Typhus in Patients With Acute Undifferentiated Febrile Illness

Tropical Medicine &International Health, EarlyView.
ABSTRACT Objective Scrub typhus is a major cause of acute undifferentiated febrile illness (AUFI) in the Asia–Pacific region. Nonspecific presentation, limited diagnostic accuracy and delayed treatment increase morbidity and mortality. This study aimed to develop a simple clinical score for early diagnosis in adults with AUFI. Methods A cross‐sectional
Wilawan Thipmontree, Ekkarat Wongsawat, Saowaluk Silpasakorn, Yupin Suputtamongkol   +3 more
wiley   +1 more source

A Fish Farmer's Encounter With Leptospirosis: A Case Report. [PDF]

Cureus, 2023
Rashid H, Omoloye AK, Abualnaja SY, Oyibo SO, Akintade OO.   +4 more
europepmc   +1 more source

Mechanisms underlying local Ca2+ signalling differences between right and left atrial myocytes at normal and increased frequencies

The Journal of Physiology, EarlyView.
Abstract figure legend Left atrial myocytes have TAT‐associated faster Ca2+ release but are more prone to maladaptation at higher frequencies due to weaker peripheral SR Ca2+ uptake and smaller trigger Ca2+ current. Abstract Changes in heart rate affect Ca2+ signalling and contractility in ventricular muscle, but the effects on atrial Ca2+ signalling ...
Joon‐Chul Kim, Hieu Trong Huynh, Phuong Kim Luong, Tran Nguyet Trinh, Yixuan Wu, Eleonora Grandi, Sun‐Hee Woo   +6 more
wiley   +1 more source

Coordinated regulation of PIEZO2 by alternative splicing, post‐translational modification, membrane trafficking and protein partners

The Journal of Physiology, EarlyView.
Abstract figure legend Regulatory mechanisms such as alternative splicing, post‐translational modification, membrane trafficking, and protein interactions control channel gating, membrane abundance, and overall activity of PIEZO2. Proper regulation supports PIEZO2‐dependent proprioceptive, somatosensory, nociceptive, pruriceptive and interoceptive ...
Eunice I. Oribamise, Qinglu Li, Mary G. Garry   +2 more
wiley   +1 more source

Algorithms in Allergy: Molecular Allergology in the Context of Animal Allergy

Allergy, EarlyView.
Christiane Hilger, Bulent E. Sekerel, Marianne van Hage, Wolfgang Hemmer, Jon R. Konradsen   +4 more
wiley   +1 more source

Subterranean environments contribute to three‐quarters of classified ecosystem services

Biological Reviews, Volume 101, Issue 3, Page 1582-1605, June 2026.
ABSTRACT Beneath the Earth's surface lies a network of interconnected caves, voids, and systems of fissures forming in rocks of sedimentary, igneous, or metamorphic origin. Although largely inaccessible to humans, this hidden realm supports and regulates services critical to ecological health and human well‐being.
Stefano Mammola, David Brankovits, Tiziana Di Lorenzo, Isabel R. Amorim, Raluca Ioana Bancila, Adrià Bellvert, Enrico Bernard, Anna Blomberg, Paulo A.V. Borges, Martina Cappelletti, Rodrigo Lopes Ferreira, Rosalina Gabriel, Diana M. P. Galassi, Laura Garzoli, Vasilis Gerovasileiou, Grant C. Hose, Kathryn L. Korbel, Simone Martino, Ana Z Miller, Nataša Mori, Veronica Nanni, Giuseppe Nicolosi, Mattia Saccò, Troy S. Sakihara, Marconi Souza Silva, Anne E. Tamalavage, Maja Zagmajster, Efraín Chávez, Christian Griebler, Pedro Cardoso, Alejandro Martínez   +30 more
wiley   +1 more source