Results 31 to 40 of about 707,618 (367)
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
IntroductionRice cultivation is of significant importance to India’s agrarian economy; however, its prolonged dominance has led to serious sustainability concerns, viz., groundwater depletion, soil compaction, fertility loss, yield stagnation ...
N. Ravisankar +12 more
doaj +1 more source
Due to complexity of smallholder farms, many times technologies with great potential fail to achieve the desired impact in leveraging productivity and profitability of the farming community.
Jashanjot Kaur +15 more
doaj +1 more source
Profitability of Organic Farming Systems [PDF]
The majority of the farmers I meet, that are interested in organic farming are financially driven. It is important that the message on financial returns from organic farming is clear.
McDonnell, James
core
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
NDICEA as a user friendly model tool for crop rotation planning in organic farming [PDF]
For organic farming systems, the challenge is to become more specific in practices to maintain high standards in sustainability. Soil processes need to be clearly understood if rotations and manure applications are to become more precise.
Koopmans, Chris J. +1 more
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Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
Web Mapping for Farm Management Information Systems: A Review and Australian Orchard Case Study
A web mapping XYZ Tile Layer Service, such as Google Earth (GE), provides an amazing resource for the visualization of spatial data against aerial and satellite imagery with global coverage, typically at a resolution finer than 5 m.
Hari Krishna Dhonju +2 more
doaj +1 more source
Screening and epitope characterization of Nidogen‐2‐specific nanobodies
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen +9 more
wiley +1 more source
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata +13 more
wiley +1 more source

