Results 171 to 180 of about 7,466 (212)
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Biochemical and Biophysical Research Communications, 1997
In this study we provide evidence for the first time that rat liver microsomal and peroxisomal fractions are able to phosphorylate free farnesol to its diphosphate ester in a CTP dependent manner. The farnesyl diphosphate (FPP) kinase activity is decreased in whole liver homogenates obtained from rats treated with cholesterol and unchanged in ...
D, Westfall +3 more
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In this study we provide evidence for the first time that rat liver microsomal and peroxisomal fractions are able to phosphorylate free farnesol to its diphosphate ester in a CTP dependent manner. The farnesyl diphosphate (FPP) kinase activity is decreased in whole liver homogenates obtained from rats treated with cholesterol and unchanged in ...
D, Westfall +3 more
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Quorum sensing by farnesol revisited
Current Genetics, 2017Quorum sensing, a form of molecular communication in microbial communities, is relatively well studied in bacterial species, but poorly understood in fungi. Farnesol, a quorum sensing molecule secreted by the opportunistic human pathogenic fungus Candida albicans, was the first quorum sensing molecule described in a eukaryotic organism.
Melanie, Polke, Ilse D, Jacobsen
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Molecular mechanisms involved in farnesol-induced apoptosis [PDF]
Cancer Letters, 2010 The isoprenoid alcohol farnesol is an effective inducer of cell cycle arrest and apoptosis in a variety of carcinoma cell types. In addition, farnesol has been reported to inhibit tumorigenesis in several animal models suggesting that it functions as a chemopreventative and anti-tumor agent in vivo.
Anton M Jetten
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Asymmetric reduction of farnesol
Tetrahedron, 1986Abstract Asymmetric hydroboration-oxidation followed by reductive deoxygenation has been used to bring about the asymmetric hydrogenation of simple trisubstituted olefins. This technique has been illustrated by the preparation of (R)-(-)-6,7,10,11-tetrahydrofarnesol.
Marc Julia, Pierre Roy
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Archives of Biochemistry and Biophysics, 1998
As farnesol may serve as a nonsterol endogenous regulator of the mevalonate pathway, the possibility that a kinase specific for its phosphorylation is present in the rat liver was investigated. In the 10,000 g supernatant of rat liver, farnesyl monophosphate was synthesized in the presence of ATP. The Km value for farnesol was 2.3 microM.
M, Bentinger +4 more
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As farnesol may serve as a nonsterol endogenous regulator of the mevalonate pathway, the possibility that a kinase specific for its phosphorylation is present in the rat liver was investigated. In the 10,000 g supernatant of rat liver, farnesyl monophosphate was synthesized in the presence of ATP. The Km value for farnesol was 2.3 microM.
M, Bentinger +4 more
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Neuropharmacological properties of farnesol in Murine model.
Iranian journal of veterinary research, 2016Research on new compounds of therapeutic value for behavioral disorders has progressed recently. Several studies have reported neuropharmacological activities of plant derived terpenes. Farnesol is a sesquiterpene whose most popular source is fruits but the anxiolytic activity for farnesol is still unknown.
Shahnouri, M. +2 more
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Effects of farnesol on the thermotropic behavior of dimyristoylphosphatidylcholine
Chemistry and Physics of Lipids, 1994Differential scanning calorimetry (DSC) and DPH fluorescence anisotropy have been used to investigate the effects of trans-trans farnesol on the physical properties of model membranes and extracted cell lipids. Farnesol was shown to have a significant effect on the gel to liquid-crystal phase transition temperature, the enthalpy of the transition and ...
O P, Bondar, G, Melnykovych, E S, Rowe
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Absence of farnesol in strawberry and hop foliage
Journal of Chemical Ecology, 1982The farnesol content of foliage has been proposed as an indicator of susceptibility to the two-spotted spider mite in various crops. The use of this chemical "marker" was investigated for strawberry and hop varieties. No farnesol was detectable in any of the varieties tested.
F A, Gunson, R F, Hutchins
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Insect Biochemistry and Molecular Biology, 2003
The oxidation of farnesol to farnesal is an important step in insect juvenile hormone (JH) biosynthesis and is mediated by one or more alcohol oxidases located within the minute endocrine gland, the corpus allatum. Because lepidopteran insects have the capacity to produce homologous JH structures, the substrate selectivity of farnesol oxidase was ...
S E, Sen +3 more
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The oxidation of farnesol to farnesal is an important step in insect juvenile hormone (JH) biosynthesis and is mediated by one or more alcohol oxidases located within the minute endocrine gland, the corpus allatum. Because lepidopteran insects have the capacity to produce homologous JH structures, the substrate selectivity of farnesol oxidase was ...
S E, Sen +3 more
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ELECTROPHILE INDUCED CYCLIZATION OF FARNESOL
Chemistry Letters, 1972Abstract The cyclization of farnesol with BF3 etherate in dichloromethane solution afforded α-cedrene, 2-epi-α-cedrene and five new hydrocarbons of muurolane type together with isomeric bisabolenes, α-curcumene and δ-selinene. The structure determination of the new compounds and the formation mechanism of cyclized products are presented.
Yoshimoto Ohta, Yoshio Hirose
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