Results 71 to 80 of about 15,163 (264)
Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids
FEBS Open Bio, EarlyView.Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão +3 more
wiley +1 more source
Arap Şiirinin Gölgesinde Serinleyen Bir Fars Şairi: Minûçihrî-yi Damgânî
, 2020 Yayın değerlendirmesini yaptığımız çalışmada Arap kültürünü şiirlerine taşıyarak diğer Fars şairlerinin aksine aykırı bir şair olarak davranan Minûçihrî-yi Damgânî’nin şiir felsefesinin kodları incelenmiştir.
Erdem Sevimli
core
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1
FEBS Open Bio, EarlyView.The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay +2 more
wiley +1 more source
, 2015 Ömer Nasuhî Bilmen, daha çok dinî ilimler alanındaki eserleriyle temayüz etmis bir dinâlimi olmakla birlikte, edebiyat alanında da çesitli eserler telif etmis bir ediptir.
Orhan BAŞARAN, Orhan BAŞARAN
core +1 more source
FEBS Open Bio, EarlyView.TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose +9 more
wiley +1 more source
Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
FEBS Open Bio, EarlyView.Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source
FEBS Open Bio, EarlyView.The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley +1 more source
The Neolithisation of Fars, Iran
, 2014 Any review of the processes of neolithisation in Fars must acknowledge, in the first instance, the fundamental paucity of data. Ironically, recent excavations that have helped to highlight some of the earliest possible 'Proto-Neolithic' and Aceramic ...
Weeks, Lloyd
core
FARS: Fuzzy Ant based Recommender System for Web Users [PDF]
, 2011 Recommender systems are useful tools which provide an adaptive web environment for web users. Nowadays, having a user friendly website is a big challenge in e-commerce technology.
Saraee, MH +3 more
core