Results 241 to 250 of about 115,762 (301)
Journal of Cellular and Molecular Medicine, Volume 30, Issue 6, March 2026.ABSTRACT The integrity of the pancreatic islet microvasculature is critical for endocrine function, yet it is progressively compromised by glucotoxicity in diabetes. While matrix metalloproteinases are implicated, the role of stromelysin‐1 as a potential upstream driver of endothelial dysfunction remains poorly defined.
Bing Wang +9 more
wiley +1 more source
Obesity Reviews, Volume 27, Issue 3, March 2026.ABSTRACT Obesity is understood as a condition driven by interactions between genetics and environmental factors. The role of CD36 in the regulation of lipid metabolism and ectopic fat accumulation emerges as a key area of interest. This review presents CD36 not only as a crucial facilitator of fatty acid uptake but also as a regulator of how and where ...
Nahuel Garcia +5 more
wiley +1 more source
Donor pretreatment with FLT-3 ligand augments anti-donor CTL, NK and LAK cell activities within liver allografts and alters the pattern of intragraft apoptotic activity [PDF]
, 1998 Chambers, FG +9 more
core
Harnessing blue light photobiomodulation for cancer therapy: Evidence from a systematic review
Photochemistry and Photobiology, Volume 102, Issue 2, Page 370-399, March/April 2026.Conventional treatments for various types of cancer are often associated with tumor recurrence and aggressiveness. Photobiomodulation with blue light (BL; 450–470 nm) emerges as a promising alternative with antitumor effects. This systematic review, with 37 in vitro and in vivo studies from 2002 to 2024, revealed that BL reduces cell viability ...
Bárbara Evelyn Santos de Lima +6 more
wiley +1 more source
Nitro-fatty acids are formed in response to virus infection and are potent inhibitors of STING palmitoylation and signaling [PDF]
, 2018 Miner, Cathrine A. +2 more
core +1 more source
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Fas, Fas ligand,and transfusion immunomodulation
Transfusion, 2001dem-onstrated that soluble HLA class I (sHLA-I) moleculesupregulate FasL expression and sFasL secretion in activatedFas-positive CD8+ T-cells and trigger their apoptosis. Thelevel of sHLA-I molecules is significantly increased in theserum of patients with an activation of their immune sys-tem, such as occurs during acute rejection of organ al-lografts,
PUPPO, FRANCESCO +4 more
openaire +3 more sources
Fas/Fas ligand and hematopoietic progenitor cells
Current Opinion in Hematology, 1998Fas antigen is a receptor that crosslinks with a ligand or antibody initiating a signal transduction cascade that leads to apoptosis. During normal hematopoiesis, Fas antigen is not expressed on CD34+ cells, including premature hematopoietic progenitor cells. Functioning Fas antigen expression is induced by several hematopoietic regulators.
Y, Niho, Y, Asano
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Structure and Function of Fas/Fas Ligand
International Reviews of Immunology, 1999Fas is a member of the TNF receptor family, that contain 2-6 cysteine-rich domains (CRDs) in their extracellular regions, a single transmembrane domain and variably sized intracytoplasmic domains. Fas belongs to a subgroup of family members that have a "death domain" near the carboxy-terminal region of the molecule.
J R, Orlinick, A K, Vaishnaw, K B, Elkon
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