Results 261 to 270 of about 115,762 (301)
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Soluble Fas and Fas Ligand in Pregnancy
Angiology, 2011The pathophysiology of pregnancy-induced hypertension and preeclampsia may involve abnormalities in placentation and the Fas/Fas ligand system. Hypothesizing abnormal plasma Fas and Fas ligand in pregnancy-induced hypertension, we recruited 20 hypertensive pregnant women at mean week 15 and 29 at week 30: 18 were studied at both time points.
Velore J, Karthikeyan +5 more
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Expression of Fas and Fas Ligand in Hodgkin's Disease
Leukemia & Lymphoma, 1999Fas and Fas ligand expression were investigated in twenty two cases of classical Hodgkin's disease (HD) by immunohistochemistry. While Reed-Sternberg (RS) cells in 7/22 (32%) cases expressed Fas ligand, reactive lymphoid cells expressed Fas ligand in only 2 (9%) cases. In 20/22 (91%) cases, the RS cells expressed Fas. A higher proportion of RS cells in
S S, Metkar +5 more
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Fas/Fas Ligand Signaling During Gestational T Cell Development
The Journal of Immunology, 1998Abstract Most thymocytes express high levels of Fas Ag (Apo-1/CD95); however, the role of Fas/Fas ligand-mediated apoptosis in thymocyte development remains unclear. During gestational development of thymocytes in C57BL/6(B6) +/+ mice, the highest levels of Fas ligand mRNA and Fas ligand protein expression were detected at gestational ...
M, Fleck +5 more
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Fas/Fas ligand-mediated apoptosis of murine Langerhans cells
Journal of Dermatological Science, 2000Epidermal Langerhans cells (LC) are potent antigen-presenting cells (APC), that play a crucial role in initiating cutaneous immune responses. The Fas/Fas ligand pathway has been implicated as an important cellular pathway in the regulation of peripheral immunity.
T, Kawamura +5 more
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Upregulation of Fas/Fas ligand in inclusion body myositis
Annals of Neurology, 1998AbstractIn inclusion body myositis, T cells invade and destroy nonnecrotic muscle fibers. The mechanism by which T cells damage muscle fibers in inflammatory myopathies is not known. In this study we have investigated the expression of Fas and Fas ligand in muscle in five patients with inclusion body myositis.
I M, Fyhr, A, Oldfors
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Immunolocalization of FAS and FAS ligand in inflammatory myopathies
Acta Neuropathologica, 2001Fas/Fas ligand (FasL) interaction can induce apoptosis, have a costimulatory role or act as a mechanism by which cytotoxic T cells produce target cell lysis. We used several commercially available antibodies to study Fas and FasL expression in polymyositis (PM), inclusion body myositis (IBM), dermatomyositis (DM) and normal controls.
J L, De Bleecker +4 more
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Apoptosis, Fas and Fas‐ligand expression in melanocytic tumors
Journal of Cutaneous Pathology, 1999Impaired regulation of apoptosis is known to be associated with the development of various forms of cancer. Fas binding ro its ligand. Fas ligand (Fas‐L), has been shown to trigger apoptosis in various cell types. Fas‐L is expressed by melanoma cells and has been suggested to play a role in melanoma escape from immune surveillance. In the present study,
E, Sprecher +8 more
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Involvement of Fas-Fas Ligand Interactions in Graft Rejection
International Reviews of Immunology, 1999The Fas/Fas ligand (FasL) pathway has been shown to be important in T lymphocyte-mediated cell death and is a key peripheral immunoregulatory mechanism that limits expansion of antigen-activated lymphocytes. The expression of Fas by commonly transplanted organs such as the heart, lung, kidney, and liver suggests that these tissues may be targets of ...
O M, Martinez, S M, Krams
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Current treatment and recent progress in gastric cancer
Ca-A Cancer Journal for Clinicians, 2021Smita S Joshi, Brian D Badgwell
exaly