Results 101 to 110 of about 291 (203)

The β integrin modulates serotonin sensitivity via NPxY motifs to regulate egg laying and mechanosensation behaviors in Caenorhabditis elegans

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background Integrin is an αβ heterodimeric receptor to the extracellular matrix; its binding to the matrix recruits focal adhesions to two NPxY motifs, the tyrosine phosphorylation sites in the cytoplasmic domain. Studies found that replacing tyrosines (Y) with phenylalanines (F) in the motif of β1 integrin displayed little developmental or ...
Josh Haram Bumm   +7 more
wiley   +1 more source

Spatiotemporal cellular dynamics of the notochord shape intervertebral disc morphogenesis in the mouse embryo through apoptosis and proliferation

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background The notochord is a midline structure essential for vertebrate embryogenesis, contributing to the development of the nervous system, digestive tract, and vertebral column. In particular, notochord signaling is indispensable for proper patterning and coordinated development of alternating vertebrae and intervertebral discs (IVDs ...
Julie Warin   +5 more
wiley   +1 more source

Impact of oral health problems on daily activities and quality of life of adolescents in Brazil. [PDF]

open access: yesRev Bras Epidemiol
Melo WF   +5 more
europepmc   +1 more source

Cardiac remodelling in the era of the recommended four pillars heart failure medical therapy

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1029-1044, April 2025.
Abstract Cardiac remodelling is a key determinant of worse cardiovascular outcome in patients with heart failure (HF) and reduced ejection fraction (HFrEF). It affects both the left ventricle (LV) structure and function as well as the left atrium (LA) and the right ventricle (RV).
Giada Colombo   +7 more
wiley   +1 more source

Metabolic abnormalities and reprogramming in cats with naturally occurring hypertrophic cardiomyopathy

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1256-1270, April 2025.
Abstract Background and aims The heart is a metabolic organ rich in mitochondria. The failing heart reprograms to utilize different energy substrates, which increase its oxygen consumption. These adaptive changes contribute to increased oxidative stress.
Qinghong Li   +12 more
wiley   +1 more source

[Analysis of Respiratory Variables During Sleep in a Sample of Women in Perimenopause: a retrospective cross-sectional study] [PDF]

open access: yesRev Fac Cien Med Univ Nac Cordoba
Caporale S   +5 more
europepmc   +1 more source

How much does the reduced electroencephalographic montage matter for seizure detection? A large‐cohort simulation study

open access: yesEpilepsia, EarlyView.
Abstract Objective Subscalp electroencephalographic (EEG) systems with few channels have emerged as promising solutions for ultra‐long‐term seizure monitoring, but the impact of montage configuration on automated seizure detection is unclear. We compared automated detection performance between full‐scalp and simulated reduced montages approximating ...
Joe Kojima   +8 more
wiley   +1 more source

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