Results 101 to 110 of about 284 (209)

New Approach Methodologies (NAMs) in Alternative Methods: A Comparative Cytotoxicity Analysis of Nanostructured Hydroxyapatite in Adipose Stem Cells Spheroids

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Toxicological assessment is essential in NP approval for health and medical applications. Although 2D cell culture has been widely used, 3D models, especially spheroids, provide better predictive value for toxicological risk assessments since they replicate complex cellular interactions more accurately.
Bianca Montenegro   +5 more
wiley   +1 more source

Clinical validation of ICNP® Terminological Subset for people with chronic kidney disease undergoing hemodialysis. [PDF]

open access: yesRev Esc Enferm USP
Silva RARD   +7 more
europepmc   +1 more source

Bioinorganic Site‐Specific Conjugation of Multi‐Arm Linkers to Create Pharmaceuticals With Targeting and Effector Functions

open access: yesJournal of the Chinese Chemical Society, EarlyView.
This Account showcases a modular, multi‐arm linker platform that decouples payload loading from antibody conjugation. By leveraging a computationally designed ACPGHA zinc‐binding motif, we demonstrate the construction of homogeneous antibody‐drug conjugates and theranostic antibody‐radionuclide conjugates with high payload loading. The multi‐arm linker
Cédric Grauffel   +2 more
wiley   +1 more source

The association between sleep and Alzheimer's disease: a systematic review. [PDF]

open access: yesDement Neuropsychol
Gonzales PNG, Villaraza SG, Rosa JCD.
europepmc   +1 more source

Reconceptualizing Aplastic Anemia—Seed, Worm, Soil

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
Aplastic anemia (AA) encompasses a group of hematological syndromes often misdiagnosed, resulting in a decrease in the overall blood cell count and representing a form of bone marrow failure. We reinterpret AA based on the “seed, worm, and soil” doctrine.
Xintong Xu   +4 more
wiley   +1 more source

Speech-language-hearing interventions in orofacial functions in individuals with Down syndrome: a scoping review. [PDF]

open access: yesCodas
Correia PRB   +6 more
europepmc   +1 more source

Lipid Metabolism, Lipogenesis, and Resistance to Third Generation EGFR‐TKIs

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
Cancer metabolism has emerged as a critical area of study in cancer research, offering insights into the complex mechanisms underlying tumor growth and development. Lipid metabolic reprogramming, especially the dynamic balance between fatty acid synthesis and fatty acid oxidation, plays significant roles in tumor progression. ABSTRACT Background Cancer
Wenhao Luo   +5 more
wiley   +1 more source

I - Evaluation of Cardiovascular Autonomic Function in Healthy Individuals. [PDF]

open access: yesArq Bras Cardiol
Maciel BC   +3 more
europepmc   +1 more source

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