Results 131 to 140 of about 808,418 (317)

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Pattern and structural detection in grayscale images through the application of quantile graphs in higher-dimensional spaces. [PDF]

Sci Rep
Vicchietti ML, Ramos FM, Campanharo ASLO.   +2 more
europepmc   +1 more source

SQUID magnetoneurography: an old-fashioned yet new tool for noninvasive functional imaging of spinal cords and peripheral nerves [PDF]

Yoshiaki Adachi, Shigenori Kawabata
openalex   +1 more source

Fashion and art cycles are driven by counter-dominance signals of elite competition: quantitative evidence from music styles [PDF]

, 2019
Peter Klimek, Robert Kreuzbauer, Stefan Thurner   +2 more
openalex   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

From function to wellbeing: healing design strategies in contemporary outdoor fashion. [PDF]

Front Psychol
Li Y, Kam S.
europepmc   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

High-capacity directional information processor using all-optical multilayered neural networks. [PDF]

Sci Adv
Wang G, Zang X, Zhang T, Tan Z, Guo Z, Zhu Y, Chen X, Zhuang S.   +7 more
europepmc   +1 more source

Amanah e-Service Quality to Improve Value Co-Creation Capability and Marketing Performance of Fashion MSMEs in Indonesia

Erna Indriyaningrum, Hendar Hendar, Alifah Ratnawati, Jefri Heridiansyah   +3 more
openalex   +2 more sources

Fully Convolutional Network with Superpixel Parsing for Fashion Web Image Segmentation

, 2016
Lixuan Yang, Helena Rodriguez, Michel Crucianu, Marin Ferecatu   +3 more
openalex   +2 more sources