Results 141 to 150 of about 1,327,517 (363)

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

open access: yesMolecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute   +17 more
wiley   +1 more source

Development of Factors for Measuring Brand Identity of Handicraft Brand for its Visual Identification

open access: yesInternational Journal of Arts Architecture & Design
Handicraft and Bihar, has a brilliant and unique connection, which adorns its aura. With the concept of brand in recent times, the handicraft sector too, needs to match with the need of the time, which is crucial for its longevity and sustenance.
Prerna Narayan, Deepak Joshi
doaj   +1 more source

Analysis of midsole gait in running shoes with various 3d printed biomimetic structure

open access: yesScientific Reports
This study aims to analyze the impact of different 3D printed biomimetic midsole structures on gait phase and gait ratio to optimize running shoe design.
Jing Li, Imjoo Jung, Sunhee Lee
doaj   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

Analysis of 3D printed longitudinal Flatfoot pads with lattice structures using various microfoaming filament

open access: yesScientific Reports
Purpose of this study is to develop longitudinal flatfoot pads using 3D printing technology for support and treatment of the arch. By applying various materials and designs to the pads, the most effective condition was confirmed.
Dikshita Chowdhury   +2 more
doaj   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

Muslim Fashions – Fashionable Muslims

open access: yes, 2005
The ISIM and the Amsterdam School for Social Science Research (ASSR) jointly organized the workshop, “Muslim Fashions - Fashionable Muslims” which was held 15–16 April. The workshop took place at Amsterdam University with additional financial support by the International Institute for Asian Studies (IIAS).
openaire   +1 more source

Home - About - Disclaimer - Privacy