Results 111 to 120 of about 1,628,370 (305)
Design of Toy Proteins Capable to Rearrange Conformations in a Mechanical Fashion
, 2002 We design toy protein mimicking a machine-like function of an enzyme. Using an insight gained by the study of conformation space of compact lattice polymers, we demonstrate the possibility of a large scale conformational rearrangement which occurs (i ...
Borovinskiy, Alexander L. +1 more
core +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
The Law, Culture, and Economics of Fashion [PDF]
Fashion is one of the world's most important creative industries. As the most immediate visible marker of self-presentation, fashion creates vocabularies for self-expression that relate individuals to society.
Evans, Lewis, Hemphill, C. Scott
core +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
ReligionsDaoist robes in the Ming Dynasty literature underwent a marked transformation from exclusive religious vestments to widespread secular attire. Originally confined to Daoist priests and sacred rites, these garments began to appear in everyday work ...
Xiangyang Bian, Menghe Tian, Liyan Zhou
doaj +1 more source
MATEC Web of Conferences, 2018 It is necessary and urgent to integrate culture and technology into the street furniture of famous cultural and historical cities. A design model of innovative cultural and technological integration is constructed by combining its internal mechanism and ...
Xia Yaqin, Yang Changchun
doaj +1 more source
The strategic challenges of academic collaboration between UK and China in relationship to employability and creative curriculum [PDF]
, 2010 The rise of the creative industries and their importance to economic growth provides the context for this paper that attempts to explore China/UK curriculum approaches to employability and entrepreneurial practices for fashion design. The paper is based
Hammond, Lynne
core
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source