Results 131 to 140 of about 405,467 (314)

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

2009 FIT Fashion Show: Knitwear, Sportswear, Menswear, pt.2

open access: yes
Knitwear, sportswear, and menswear designed by graduating students in FIT's BFA fashion design program.

core  

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

The role of Fashion Photography in Fashion Design field

open access: yesJournal of Architecture, Art & Humanistic Science, 2017
The brand catalogue as one of the most important types of fashion photography has a big role in the field of fashion design, styling and branding. It helps in fashion spread, trend analysis and styling and displaying brand identity. But the problem summered in attributing the fashion catalogue mission to the photographer or the designer.
Doha El Demedash   +2 more
openaire   +1 more source

Fashion Futuring : rethinking sustainable fashion design

open access: yes, 2021
The paper investigates the possibility to re-imagine fashion design in a sustainable direction and to conceive alternatives to the current unsustainable growth of which fashion has been a carrier in recent decades. The paper relies on the emerging design-theory-based concept of “futuring”, which concerns ecology, sustainability, and social innovation ...
Vaccari, Alessandra, Vanni, Ilaria
openaire   +1 more source

BFA Fashion Show 2011: The Future of Fashion (part 1 of 5)

open access: yes
The best work of FIT’s graduating fashion design students is presented every spring in a professional runway show. Specializations include sportswear, special occasion, knitwear, intimate apparel, and children’s wear.The 2011 award winners: Jinsol Kim ...

core  

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Deconstruction fashion design through an analysis of Korean fashion design

open access: yesThe Research Journal of the Costume Culture, 2022
Minjae Han, Younhee Lee
openaire   +1 more source

BFA Fashion Show 2011: The Future of Fashion (part 5 of 5)

open access: yes
The best work of FIT’s graduating fashion design students is presented every spring in a professional runway show. Specializations include sportswear, special occasion, knitwear, intimate apparel, and children’s wear.The 2011 award winners: Jinsol Kim ...

core  

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

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