Results 151 to 160 of about 405,467 (314)

2010 FIT Fashion Show part 2: Intimate Apparel

open access: yes
Intimate Apparel designed by graduating students in FIT's BFA fashion design program.

core  

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

2010 FIT Fashion Show part 1: Special Occasion and Menswear

open access: yes
Special Occasion and Menswear designed by graduating students in FIT's BFA fashion design program.

core  

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

open access: yesMolecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi   +14 more
wiley   +1 more source

2010 FIT Fashion Show part 5: Knitwear, Sportswear, Menswear

open access: yes
Knitwear, Sportswear, and Menswear designed by graduating students in FIT's BFA fashion design program.

core  

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

DESIGN FOR SUSTAINABLE FASHION: A SUSTAINABILITY DESIGN-ORIENTING TOOL FOR FASHION

open access: yes, 2019
Fashion is recognised as one of the most unsustainable systems, being characterized by both severe environmental impacts and unfair working conditions. In this framework, the article describes the design support tool called Sustainability design-orienting scenario for fashion and its development process.
B. Azzi, C. Vezzoli, G. M. Conti
openaire   +1 more source

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