Results 161 to 170 of about 1,628,370 (305)

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Analyzing the adoption of AIGC tools in fashion design: An S-O-R framework integrating task-technology fit. [PDF]

PLoS One
Yang M, Jin J.
europepmc   +1 more source

Using Collective Intelligence to Route Internet Traffic

, 1999
A COllective INtelligence (COIN) is a set of interacting reinforcement learning (RL) algorithms designed in an automated fashion so that their collective behavior optimizes a global utility function.
Frank, Jeremy, Tumer, Kagan, Wolpert, David H.   +2 more
core   +3 more sources

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

New Article of Clothing translates the Mood of an Individual [PDF]

It is a universal phenomenon that dressing/clothing has an effect on the personality of an individual. One’s attire/dressing is said to be an important part of the personality representation as it gives the first impression on the others.
Hasan, Syed Akif, Osman, Ms. Amber, Subhani, Muhammad Imtiaz   +2 more
core   +1 more source

NKCC1: A key regulator of glioblastoma progression

Molecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen, Diana Freitag, Madlen Haase, Christian Senft, Falko Schwarz, Silke Keiner   +5 more
wiley   +1 more source

Analysis of clothing pressure based on material of virtually-fitted swimsuits and wearer body type and movement using 3D fashion design software. [PDF]

PLoS One
Kim J, Chae Y.
europepmc   +1 more source

Design configuration in fashion and design industries

, 2005
Depuis une vingtaine d'années, les industries de la Mode et de l'habillement ont été marquées par une mutation profonde de leurs chaînes de valeur. Elles sont passées d'un modèle taylorien d'organisation du travail à une configuration de circuit court s ...
Abecassis, Céline, Benghozi, Pierre-Jean   +1 more
core  

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

The application of hierarchical perception technology based on deep learning in 3D fashion design. [PDF]

Heliyon
Cong X, Zhang W.
europepmc   +1 more source