Results 91 to 100 of about 246,562 (305)
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
John Bartlett at the Queer History of Fashion Symposium
John Bartlett, fashion designer, presents "My Life as a Gay Designer" at The Museum at FIT's 13th fashion symposium, A Queer History of Fashion, held November 8-9, 2013. This is an edited version of the full talk, which will be available for check out at
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Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Les médias audiovisuels, l’autre vitrine de la création et des créateurs de mode
The history and the economy of fashion are both closely linked to those of the media that it is difficult not to take those into consideration when drawing up an inventory of fashion heritage. The collections of the French national audiovisual institute (
Tiziana de Santis, Géraldine Poels
doaj +1 more source
Ralph Rucci at the Queer History of Fashion Symposium
Fashion designer Ralph Rucci presents “The Greatest Gay Fashion Designers” at The Museum at FIT’s 13th fashion symposium, A Queer History of Fashion, held November 8-9, 2013. This is an edited version of the full talk, which is available for check out at
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Raiding the Past, Designing for the Future
Academic staff involved with fashion teaching are often concerned at the level of research engagement by students; much of it tends to be over-reliant on Internet search engines and magazines.
Almond, Kevin, Almond, K
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CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Professor Christopher Breward at the Queer History of Fashion Symposium
Professor Christopher Breward, professor of cultural history at the University of Edinburgh, presents the paper "Couture as Queer Auto/Biography" at The Museum at FIT's 13th fashion symposium, A Queer History of Fashion, held November 8-9, 2013.
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Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source

