Results 91 to 100 of about 246,562 (305)

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

John Bartlett at the Queer History of Fashion Symposium

open access: yes
John Bartlett, fashion designer, presents "My Life as a Gay Designer" at The Museum at FIT's 13th fashion symposium, A Queer History of Fashion, held November 8-9, 2013. This is an edited version of the full talk, which will be available for check out at

core  

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Les médias audiovisuels, l’autre vitrine de la création et des créateurs de mode

open access: yesIn Situ
The history and the economy of fashion are both closely linked to those of the media that it is difficult not to take those into consideration when drawing up an inventory of fashion heritage. The collections of the French national audiovisual institute (
Tiziana de Santis, Géraldine Poels
doaj   +1 more source

Ralph Rucci at the Queer History of Fashion Symposium

open access: yes
Fashion designer Ralph Rucci presents “The Greatest Gay Fashion Designers” at The Museum at FIT’s 13th fashion symposium, A Queer History of Fashion, held November 8-9, 2013. This is an edited version of the full talk, which is available for check out at

core  

Raiding the Past, Designing for the Future

open access: yes, 2013
Academic staff involved with fashion teaching are often concerned at the level of research engagement by students; much of it tends to be over-reliant on Internet search engines and magazines.
Almond, Kevin, Almond, K
core  

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Professor Christopher Breward at the Queer History of Fashion Symposium

open access: yes
Professor Christopher Breward, professor of cultural history at the University of Edinburgh, presents the paper "Couture as Queer Auto/Biography" at The Museum at FIT's 13th fashion symposium, A Queer History of Fashion, held November 8-9, 2013.

core  

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

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