Results 101 to 110 of about 9,648,146 (309)

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Dr. Valerie Steele at the Queer History of Fashion Symposium

open access: yes
Dr. Valerie Steele, director and chief curator of The Museum at FIT, presents "A Queer History of Fashion" at The Museum at FIT's 13th fashion symposium, held November 8-9, 2013.

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Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

open access: yesMolecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic   +15 more
wiley   +1 more source

Football Equipment as a Subject of Socio-Cultural Analysis: Possibilities and Problems of the Research Field

open access: yesСоциология власти
The history of sports equipment is an under-researshed topic in history of sport as well as fashion studies. This article is dedicated to the socio-cultural studies of the culture of sport's fashion and design en general and football equipment in ...
Ekaterina A. Kulinicheva
doaj  

Interview with Regina Root

open access: yesAcervo
Regina A. Root (raroot@wm.edu) is Professor of Hispanic Studies at William & Mary, the historic university in Williamsburg, Virginia. She is an international expert known for her work on fashion, textiles, and Latin American cultural production.
Maria do Carmo Teixeira Rainho   +1 more
doaj   +1 more source

Professor Christopher Breward at the Queer History of Fashion Symposium

open access: yes
Professor Christopher Breward, professor of cultural history at the University of Edinburgh, presents the paper "Couture as Queer Auto/Biography" at The Museum at FIT's 13th fashion symposium, A Queer History of Fashion, held November 8-9, 2013.

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Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

2007 FIT Fashion Show: Knitwear

open access: yes
FIT's fashion design seniors are the "Rising New Stars 2007." Student designs in knitwear are presented at the annual student fashion ...

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Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

open access: yesMolecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim   +7 more
wiley   +1 more source

2008 FIT Fashion Show: Sportswear

open access: yes
Sportswear designed by graduating students in FIT's BFA fashion design program.

core  

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