Results 121 to 130 of about 246,562 (305)

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Exhibiting Fashion Symposium: Judith Clark "Experimentation in Fashion Exhibitions"

open access: yes
The Museum at FIT presented Exhibiting Fashion, its twenty-first academic symposium on Friday, March 8, 2019. This symposium explored the history of fashion curating, the different ways fashion is displayed in museum settings, and how national and ...

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Fashion and desire in an ecologically sustainable world [PDF]

open access: yes, 2012
The popularity of sustainability has encroached on the fashion industry and as such, there are currently an increasing number of fashion designers and brands who profit from the sales of “sustainable fashion.” The fashion industry capitalises upon
Latoya Voogt
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Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

Liz Collins at the Queer History of Fashion Symposium

open access: yes
Liz Collins, New York designer and artist, presents "Art Dykes and Hag Fags: An Insider's View of Queer Style Icons" at The Museum at FIT's 13th fashion symposium, A Queer History of Fashion, held November 8-9, 2013. This is an edited version of the full

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Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Dr. Deirdre Clemente at the Queer History of Fashion Symposium

open access: yes
Dr. Deirdre Clemente, assistant professor at the University of Nevada, Las Vegas, presents "Life in the Closet: Deconstructing Liberace's Wardrobe" at The Museum at FIT's 13th fashion symposium, A Queer History of Fashion, held November 8-9, 2013.

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Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

open access: yesMolecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy   +10 more
wiley   +1 more source

Hal Rubenstein at the Queer History of Fashion Symposium

open access: yes
Hal Rubenstein, an authority on celebrity style who has appeared on the Today show and The View, asks "Do Gay Clothes Have More Fun?" at The Museum at FIT's 13th fashion symposium, A Queer History of Fashion, held November 8-9, 2013.

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