Results 101 to 110 of about 848,172 (306)
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Challenging body shaming with grading techniques in the fashion industry
Social Sciences and Humanities OpenBody shaming remains a prevalent concern in the fashion business, as conventional beauty standards sometimes exclude persons with varied body shapes.
Agus Hery Supadmi Irianti +3 more
doaj +1 more source
The Role of Fashion Bloggers in Fashion Marketing Communication
Informacijos Mokslai, 2019 Because of digitization and internet development that took place in the 21st century, fashion industry has been consistently encountering various challenges.
Akvilė Mickevičiūtė +1 more
doaj +1 more source
The perception of circular economy in the framework of fashion industry. [PDF]
Waste Manag Res, 2023 Papamichael I +5 more
europepmc +1 more source
Firm Entry and Institutional Lock-in: An Organizational Ecology Analysis of the Global Fashion Design Industry [PDF]
Few industries are more concentrated than the global fashion industry. We analyse the geography and evolution of the ready-to-wear fashion design industry by looking at the yearly entry rates following an organizational ecology approach.
Koen Frenken, Rik Wenting
core
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Design Imitation in the Fashion Industry [PDF]
The paper deals with the imitation of fashion products, an issue that attracts considerable interest in practice. Copying of fashion originals is a major concern of designers and, in particular, their financial backers.
Andrea Di Liddo, Steffen Jrgensen
core
A Sense of Duty: Retiring the Special Relationship Rule and Holding Gun Manufacturers Liable for Negligently Distributing Guns [PDF]
, 2000 In response to recent litigation brought against the gun industry on behalf of individuals and municipalities victimized as a result of the negligent marketing, design, and distribution of guns, the gun industry has argued that they cannot be held ...
Bhowmik, Rachana +3 more
core +1 more source