Results 111 to 120 of about 848,172 (306)

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

AI tools and fashion design education: instructor perspectives on student challenges and design process tool support

open access: yesFashion and Textiles
Despite growing interest in artificial intelligence (AI) in higher education, research on its pedagogical integration in fashion design education remains limited, with most studies focusing on the technical aspects of AI tools rather than their ...
Hyosun An, Minjung Park
doaj   +1 more source

INDUSTRI KREATIF FASHION

open access: yesJUSS (Jurnal Sosial Soedirman), 2017
The article deals with the phenomenon of creative industries in Purwokerto, particularly fashion. It focuses on the survival strategy and idealism of Kidal Kolektif, one of fashion outlets in Purwokerto. This article selects to analyze Kidal Kolektif as the outlet has uniqueness incomparable to other fashion outlets in Purwokerto.
Hendri Restuadhi, Restu Utami
openaire   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Role of Culture in Transformation Processes of the Fashion Industry Ecosystem

open access: yesКультура і мистецтво у сучасному світі
The aim of the article is to determine the influence of culture on the sustainability aspects of the fashion industry. To define this influence, an ecosystem approach is applied, where a three-level hierarchy of ecosystems represents the fashion ...
Iryna Hardabkhadze
doaj   +1 more source

Far-Infrared Emission Characteristics and Wear Comfort Property of ZrC-Imbedded Heat Storage Knitted Fabrics for Emotional Garments

open access: yesAUTEX Research Journal, 2017
This study examined the far-infrared emission characteristics and wear comfort properties of ZrC-imbedded heat storage knitted fabrics. For this purpose, ZrC-imbedded, heat storage PET (polyethylene terephthalate) was spun from high-viscosity PET with ...
Kim Hyun Ah, Kim Seung Jin
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

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