Helminthic larval stage induces cellular apoptosis via caspase 9-mediated mitochondrial dysfunction. [PDF]
Sternkopf LE +15 more
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Genotyping of the gene polymorphisms FASL 844C/T and FAS 670A/G in patients with idiopathic infertility in Iraq. [PDF]
Manshd AA, Alaboudi MA, Al-Raad AA.
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Fatty acid uptake mediated by FABP4 promotes the formation of CD8<sup>+</sup>T cell senescence through lipid peroxidation in the adipocyte-rich microenvironment of Ovarian Cancer. [PDF]
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Platelet aggregation elicits FasL expression and hepatocyte apoptosis in sinusoidal obstruction syndrome. [PDF]
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Immune Mechanisms and Pain in Intervertebral Disc Degeneration. [PDF]
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IL-21 Selectively Augments Cytotoxic Potential of Antigen-Activated MAIT Cells. [PDF]
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The Role of Nitric Oxide in HSV-1 Infection: The Use of an Inducible Nitric Synthase Inhibitor Aminoguanidine to Treat Neuroinflammation. [PDF]
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AbstractFas ligand (FasL) is best known for its ability to induce cell death in a wide range of Fas-expressing targets and to limit inflammation in immunoprivileged sites such as the eye. In addition, the ability of FasL to induce a much more extensive list of outcomes is being increasingly explored and accepted. These outcomes include the induction of
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FasL (CD95L) is a well-known and well-characterized death-inducing ligand. Spontaneous mutations in FasL and its cognate receptor Fas (CD95) have helped understand the role of these molecules in the disease. Once thought to be mainly involved in the homeostasis of immune system, the territory of FasL regulation has been expanded to angiogenesis and ...
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Fas-FasL in Hashimoto's Thyroiditis
Journal of Clinical Immunology, 2001Hashimoto's thyroiditis is a common chronic autoimmune disease characterized by the loss of thyroid follicular cells (thyrocytes) that are gradually replaced by lymphocytic infiltration and diffuse fibrosis. These morphological findings suggested that autoreactive T-cell clones were responsible for thyrocyte destruction and hypothyroidism through ...
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