Results 41 to 50 of about 13,580 (276)

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

Impulsive disturbances of the geomagnetic field as a cause of induced currents of electric power lines

open access: yesJournal of Space Weather and Space Climate, 2019
Geomagnetically induced currents (GICs) represent a significant challenge for society on a stable electricity supply. Space weather activates global electromagnetic and plasma processes in the near-Earth environment, however, the highest risk of GICs is ...
Belakhovsky Vladimir   +4 more
doaj   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

open access: yesMolecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece   +18 more
wiley   +1 more source

Dynamical Change of Signal Complexity in the Brain During Inhibitory Control Processes

open access: yesEntropy, 2015
The ability to inhibit impulses and withdraw certain responses are essential for human’s survival in a fast-changing environment. These processes happen fast, in a complex manner, and require our brain to make a fast adaptation to inhibit the impulsive ...
Shih-Lin Huang   +2 more
doaj   +1 more source

Broadband onset inhibition can suppress spectral splatter in the auditory brainstem. [PDF]

open access: yesPLoS ONE, 2015
In vivo intracellular responses to auditory stimuli revealed that, in a particular population of cells of the ventral nucleus of the lateral lemniscus (VNLL) of rats, fast inhibition occurred before the first action potential.
Martin J Spencer   +6 more
doaj   +1 more source

Bearing Fault Diagnosis Based on Energy Spectrum Statistics and Modified Mayfly Optimization Algorithm

open access: yesSensors, 2021
This study proposes a novel resonance demodulation frequency band selection method named the initial center frequency-guided filter (ICFGF) to diagnose the bearing fault. The proposed technology has a better performance on resisting the interference from
Yuhu Liu   +3 more
doaj   +1 more source

Effect of moisture on electrical response of sand and clay under high impulse voltage applications [PDF]

open access: yes, 2017
Soil plays an important role in ground designing. Engineers normally consider only soil resistivity under normal or steady state condition when designing the grounding system. Under certain circumstances such as lightning, electrical response of the soil
Gomes, Chandima   +2 more
core  

The Effect of Ladder Drill Side Right In Training on Increasing the Agility of the Futsal Team of SMKN 1 Kandangan [PDF]

open access: yes
This study aims to determine the effect of ladder drill side right in training on improving agility in the futsal team of SMK Negeri 1 Kandangan. Pre-experimental was used as the research method and Pretest and Posttest in One Group as the research ...
Rachman, Aryadi   +2 more
core   +2 more sources

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

Fast impulsive reconnection and current sheet intensification due to electron pressure gradients in semi‐collisional plasmas

open access: yesGeophysical Research Letters, 1996
A numerical simulation of forced reconnection and current sheet growth due to inward boundary flows in semi‐collisional plasmas is presented, and contrasted with the results of an incompressible resistive MHD simulation in the high‐Lundquist‐number regime.
Z. W. Ma, A. Bhattacharjee
openaire   +1 more source

Home - About - Disclaimer - Privacy