Remote Assessment of Ataxia Severity in SCA3 Across Multiple Centers and Time Points
ABSTRACT Objective Spinocerebellar ataxia type 3 (SCA3) is a genetically defined ataxia. The Scale for Assessment and Rating of Ataxia (SARA) is a clinician‐reported outcome that measures ataxia severity at a single time point. In its standard application, SARA fails to capture short‐term fluctuations, limiting its sensitivity in trials.
Marcus Grobe‐Einsler +20 more
wiley +1 more source
The Brief Case: Danger is afoot! [PDF]
Darrah EJ, Wood M, Frank MO, Liesman RM.
europepmc +1 more source
Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease
ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito +14 more
wiley +1 more source
Biochemical Upcycling of PET via Glycolysis and Engineered Microbial Consortia. [PDF]
Molpeceres-García FJ +4 more
europepmc +1 more source
CX3CL1 in Early Detection of Alzheimer's Disease: Plasma Dynamics Across Age and Disease Stages
ABSTRACT Backgrounds Alzheimer's disease (AD) is characterized by amyloid‐beta plaques, tau tangles, and neuroinflammation. C‐X3‐C motif chemokine ligand 1 (CX3CL1, also known as fractalkine), a neuroimmune chemokine implicated in AD pathogenesis, shows inconsistent alterations in plasma/serum across studies.
Ling Wang +6 more
wiley +1 more source
Prevalence and Determinants of Fast Food Consumption Among Medical Sciences Students in Kermanshah, Iran. [PDF]
Janatolmakan M +4 more
europepmc +1 more source
Data-Driven System Matrix Manipulation Enabling Fast Functional Imaging in Tomography. [PDF]
Hu P, Tong X, Lin L, Wang LV.
europepmc +1 more source
An improved Newman fast division algorithm based on multi-factor correlation for dynamic traffic sub-region control. [PDF]
Tian X, Ding J, Liu H, Deng H.
europepmc +1 more source
Oral amino acid tracer delivery detects feeding and exercise changes in myofibrillar protein synthesis rates in male adults. [PDF]
Mazzulla M +7 more
europepmc +1 more source

