Results 91 to 100 of about 11,417,388 (340)
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Fast distributed algorithms for Lp-type problems of low dimension [PDF]
, 2019 In this paper we present various distributed algorithms for LP-type problems in the well-known gossip model. LP-type problems include many important classes of problems such as (integer) linear programming, geometric problems like smallest enclosing ball
Struijs, Martijn +3 more
core +1 more source
Fast algorithm for efficient simulation of quantum algorithm gates on classical computer [PDF]
Journal of Systemics, Cybernetics and Informatics, 2004 The general approach for quantum algorithm simulation on classical computer is introduced.
Sergey Panfilov +3 more
doaj
HEALPix: A Framework for High-Resolution Discretization and Fast Analysis of Data Distributed on the Sphere [PDF]
, 2004 HEALPix—the Hierarchical Equal Area isoLatitude Pixelization—is a versatile structure for the pixelization of data on the sphere. An associated library of computational algorithms and visualization software supports fast scientific applications ...
K. Gorski +6 more
semanticscholar +1 more source
A fast quadtree normalization algorithm [PDF]
Pattern Recognition Letters, 1994 Ang, C.-H. and H. Samet, A fast quadtree normalization algorithm, Pattern Recognition Letters 15 (1994) 5763. A region quadtree representation of an image can be normalized thereby yielding a quadtree that contains the least number of nodes in O(s 2 log2 s) time where s is the length of the grid.
Ang, C.-H., Samet, H.
openaire +1 more source
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Design of competitive paging algorithms with good behaviour in practice [PDF]
, 2013 Paging is one of the most prominent problems in the field of online algorithms. We have to serve a sequence of page requests using a cache that can hold up to k pages. If the currently requested page is in cache we have a cache hit, otherwise we say that
Negoescu, Andrei Laurian
core
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
A comprehensive evaluation of alignment algorithms in the context of RNA-seq. [PDF]
, 2012 Transcriptome sequencing (RNA-Seq) overcomes limitations of previously used RNA quantification methods and provides one experimental framework for both high-throughput characterization and quantification of transcripts at the nucleotide level.
Friedel, Caroline C. +8 more
core +2 more sources