Results 61 to 70 of about 5,060,458 (305)

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

A Hierarchical Navigation Strategy of EV Fast Charging Based on Dynamic Scene

IEEE Access, 2019
With the development of the EV industry, the growing demand for EV fast charging load has brought enormous impact on the power system. Due to the unbalance of charging time distribution and the high power of EV fast charging, the difference between peak ...
Fangzhou Xia, Hongkun Chen, Lei Chen, Xinyu Qin   +3 more
doaj   +1 more source

Energy Management of Fast Charging and Ultra-Fast Charging Stations With Distributed Energy Resources

IEEE Access
Dependence on the depleting fossil fuels, particularly in the transportation sector, calls for sustainable, green solutions such as electrification, which address the challenges of providing alternate sources of power at low emissions. Electric vehicles are the centerpiece of the transportation electrification sector.
Sony Susan Varghese, Syed Qaseem Ali, Geza Joos   +2 more
openaire   +2 more sources

Discerning protein pools by selective staining with self‐labeling tags

FEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Multi-mode collaborative optimization of electric vehicle charging load characteristics in tourist cities: An Anshun case study

AIP Advances
This study developed an electricity consumption behavior model for electric vehicles during tourist and non-tourist seasons in Anhui based on the probability density algorithm. The daily load characteristics of three charging modes—regular charging, fast-
Weimin Wu, Zhaoqin Liu, Yun Wu, Wanjun Yan, Xiufan Yang   +4 more
doaj   +1 more source

Macroporous Directed and Interconnected Carbon Architectures Endow Amorphous Silicon Nanodots as Low-Strain and Fast-Charging Anode for Lithium-Ion Batteries

Nano-Micro Letters
MPCF@VG@SiNDs/C, constructed by uniformly dispersing amorphous Si nanodots in carbon nanospheres that are welded on the wall of the macroporous carbon frameworks by vertical graphene, is synthesized and has achieved a few kilogram production per batch ...
Zhenwei Li, Meisheng Han, Peilun Yu, Junsheng Lin, Jie Yu   +4 more
semanticscholar   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Highly‐Entangled Hydrogel Electrolyte for Fast Charging/Discharging Properties in Aqueous Zinc Ion Batteries

Advanced Functional Materials
Aqueous zinc ion batteries coupling with conventional hydrogel electrolyte have the advantages of high safety, low cost, and simple manufacturing process while they are difficult for fast charging/discharging application scenarios due to the sluggish ...
Zhaoxi Shen, Yu Liu, Zhongheng Li, Ziqing Tang, Jun Pu, Lei Luo, Yu Ji, Junpeng Xie, Zheng Shu, Yagang Yao, Ning Zhang, Guo Hong   +11 more
semanticscholar   +1 more source