Results 71 to 80 of about 5,060,458 (305)

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Analysis and modelling of DC fast-charging profiles of heterogeneous EVs

Transportation Engineering
Electric vehicles (EVs) fast-charging is a crucial enabler for the smooth electrification of the private mobility. In the available literature, studies related to fast-charging have been mainly focusing on the optimal sizing/placement and/or operation of
Toni Simolin, Pertti Järventausta, Mario Paolone   +2 more
doaj   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

Fast EV charging station integration with grid ensuring optimal and quality power exchange

Engineering Science and Technology, an International Journal, 2019
Increased problem of air pollution has led automotive industry to develop clean and efficient fuel based transportation and Electric Vehicles (EVs) appear to be the most suitable alternatives to conventional IC engine based vehicles. Fast charging of EVs
Wajahat Khan, Furkan Ahmad, Mohammad Saad Alam   +2 more
doaj   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Expanding the Fast Charging Network [PDF]

World Electric Vehicle Journal, 2016
Oregon has more DC Fast Chargers (DCFC) for electric vehicles per capita than any other US region. This network has played a major role in making Oregon one of the strongest markets for electric vehicle sales in the US, despite the lack of a state purchase incentive.
openaire   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

On-Road Wireless EV Charging Systems as a Complementary to Fast Charging Stations in Smart Grids

World Electric Vehicle Journal
Electric vehicle (EV) users have the flexibility to fulfill their charging needs using either high-speed charging stations or innovative on-road wireless charging systems, ensuring uninterrupted travel to their destinations.
Fawzi Alorifi, Walied Alfraidi, Mohamed Shalaby   +2 more
doaj   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

FEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta, Nidhi Yadav, Subhasmita Das, R. Rajendra Kumar Reddy, Nupur Sharma, Amol Ratnakar Suryawanshi, Jaswinder Singh Maras, Ranjan Kumar Nanda   +7 more
wiley   +1 more source

Modes of fast charging

, 2018
Fast charging is usually seen as a means to facilitate long distance driving for electric vehicles and roll-out therefore often happens with corridors in mind. Due to limited charging speeds, EV drivers usually tend to charge at home or work when the car is parked for a longer period to avoid unnecessarily time loss.
Wolbertus, R., Helmus, J., Maase, S.J.F.M., van den Hoed, R.   +3 more
openaire   +2 more sources