Results 91 to 100 of about 1,029,548 (340)

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Analysis of Fast Fashion Brand Marketing Innovation Strategy- -Taking SHEIN as an example [PDF]

open access: yesSHS Web of Conferences
With the rapid progress of globalization and Internet technology, China’s fast fashion industry market is becoming more and more prosperous, and various fast fashion brands emerge in an endless stream. In this context, SHEIN stands out in the competitive
Wu Yaheng, Yang Chunmin
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

A study of purchase intention of international fast-fashion brands of Malaysian Gen Y consumers [PDF]

open access: yes, 2018
Generation Y consumers have become increasingly fashion conscious, contributing to the growth of the fashion industry particularly with a keen interest in international fast-fashion bands. Underlined by the consumer behaviour expectancy theory and theory
Lee, Wan Shan, Ong, Derek Lai Teik *
core  

A fast GPU Monte Carlo Radiative Heat Transfer Implementation for Coupling with Direct Numerical Simulation

open access: yes, 2018
We implemented a fast Reciprocal Monte Carlo algorithm, to accurately solve radiative heat transfer in turbulent flows of non-grey participating media that can be coupled to fully resolved turbulent flows, namely to Direct Numerical Simulation (DNS). The
Pecnik, Rene, Silvestri, Simone
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Research on the marketing strategies of mainstream fast fashion and luxury clothing brands based on the 4P model: A case study of Zara and Prada [PDF]

open access: yesSHS Web of Conferences
With the continuous improvement of people’s living standards and the development of the fashion industry, people’s demand for different styles of fashion is also increasing.
Wang Ziying
doaj   +1 more source

On the non-Poissonian repetition pattern of FRB121102

open access: yes, 2018
Rhe Fast Radio Burst FRB121102 has been observed to repeat in an irregular fashion. Using published timing data of the observed bursts, we show that Poissonian statistics are not a good description of this random process.
Opperman, Niels, Pen, Ue-Li, Yu, Hao-Ran
core   +1 more source

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