Results 51 to 60 of about 80,232 (212)
Factors Affecting Underweight and Obesity Among Elementary School Children in South Korea
Purpose: The purpose of the study was to determine factors associated with underweight and obesity in elementary school children in Korea. Methods: Study participants included 4,895 children attending 59 elementary schools across Korea.
GyuYoung Lee, RN, PhD +1 more
doaj +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Associations between dietary patterns and metabolic syndrome in adolescents
Objective. Evaluate association of dietary patterns with metabolic syndrome (MetS) and metabolic markers. Materials and methods. 654 adolescents from Guadalajara, Jalisco, participated in a cross-sectional study.
Guadalupe Ramírez-López +2 more
doaj +1 more source
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Adolescents’ excessive consumption of sugar-sweetened beverages (SSBs) has become a global concern due to its detrimental effects on health. We explored the prevalence and associated factors of the consumption of SSB in high-school children in the ...
Deldar Morad Abdulah +2 more
doaj +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
BackgroundThe rise of ultra-processed foods (UPFs) poses a significant challenge for chronic disease management. Culinary competence (CC) has been described as a behavioral characteristic associated with higher quality dietary patterns.
Adrián Idoate-Bayón +12 more
doaj +1 more source
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Dietary and lifestyle habits amongst adolescents in Bahrain
Changes in dietary habits and lifestyle are considered the main factors associated with several diet-related diseases in the Arab Gulf countries. The aim of this study was, therefore, to describe the dietary and lifestyle habits amongst adolescents in ...
Khaldoon Al-Roomi +3 more
doaj +1 more source

